Wemeijer, T. (Tessa) (2016) Correlation Electrocardiogram repolarisation measures and Left Ventricular Ejection Fraction in Acute Cardiac Syndrome patients after Percutaneous Coronary Intervention. thesis, Medicine.
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Abstract
2 Abstract Background: A number of studies have examined individual measures of repolarisation abnormalities from the ECG T-wave, and suggested that these may predict risk of sudden cardiac death. However, the relationship between these different parameters has not been explored, and the frequency of abnormal values in a population following myocardial infarction is not clear. Objective: This study examined the relationship between a number of repolarisation measures derived from the electrocardiogram T-wave in patients after a acute myocardial infarction, and their relationship to LVEF. Methods: A total of 121 AMI patients (mean age 65.9 ± 10.8 years) were included after revascularisation with PCI. A five minutes resting simultaneous 12-lead digital ECG recording was taken from all patients, within 1-4 hours after procedure. Using LabView8.5, eight T-wave parameters were estimated and compared mutually and among LVEF. Results: The 8 T-wave parameters were not strongly correlated with each other, with one moderate correlation and four weak correlations. The majority of patients (75.2%) could be classified as having elevated risk of sudden cardiac death on the basis of at least one T wave measure, and 50.4% had 2 or more high risk T wave measures. LVEF was estimated in 49 patients. This number was too small to perform significant analysis, but data showed the possibility of T-wave parameters being independent and containing a predictive value. Conclusions: Using multiple parameters may be superior to a single metric in the stratification of sudden cardiac death after acute presentation of a myocardial infarction. Further investigation is desired to confirm this assumption.
| Item Type: | Thesis (Thesis) |
|---|---|
| Supervisor name: | Faculty supervisor and Nieuwland, Dhr. W. and Cardiologist Universitair Medical Centrum Groningen and Groningen, the Netherlands |
| Supervisor name: | Second / locally supervisor and Larsen, Dhr. P. and Professor University of Otago and Wellington Regional Hospital, New Zealand |
| Faculty: | Medical Sciences |
| Date Deposited: | 25 Jun 2020 10:48 |
| Last Modified: | 25 Jun 2020 10:48 |
| URI: | https://umcg.studenttheses.ub.rug.nl/id/eprint/975 |
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