Noordermeer, B. (Bas) (2013) “Iatrogeen galwegletsel na cholecystectomie”. thesis, Medicine.
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Abstract
Objective: Some patients, who had surgical intervention for iatrogenic bile duct injuries after cholecystectomy, still have health issues after a follow-up period of at least two years. The aim of this study was to identify factors why these patient still have health problems and others recover uncomplicated. Method: This study was a retrospective cohort study with patients who received iatrogenic bile duct injuries after cholecystectomy in the period 1992-2010. De study population consisted of 113 patients from 18 years or older, who were referred to the University Medical Center Groningen because of the bile duct injury or patients who received the bile duct injury in the UMCG. Only endoscopic treated patients were excluded. Univariate analyses were used to find significant differences between the two groups. Then a multivariate analysis was used to find independent variables who are associated with the chance to keep health issues after 2 years or recover uncomplicated. Results: Six variables were found with a significant difference (p≤0,05) between the groups with and without complaints after at least two years of follow-up, after univariate analyses of 98 variables. The multivariate analysis showed five independent variables who are associated with the chance to remain health issues of to recover uncomplicated. De associating factors were age during cholecystectomy (p=0,031), moment of diagnosis of iatrogenic bile duct injury (p=0,001), type of bile duct injury according to Hannover classification (p=0,038), receiving hepticojejunostomy or not (0=0,003) and receiving a therapeutic ERCP or not (p=0,001). Conclusion: There are five identified factors in patients, who had surgical intervention for iatrogenic bile duct injuries after cholecystectomy, associated with the chance of remaining health issues after a follow-up of at least two years or recover uncomplicated.
| Item Type: | Thesis (Thesis) |
|---|---|
| Supervisor name: | Porte, Prof. Dr. R.J. and Boonstra, E.A. |
| Faculty: | Medical Sciences |
| Date Deposited: | 25 Jun 2020 10:48 |
| Last Modified: | 25 Jun 2020 10:48 |
| URI: | https://umcg.studenttheses.ub.rug.nl/id/eprint/954 |
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