Joustra, M.L. (2014) Physical activity and sleep duration in chronic fatigue syndrome and fibromyalgia. thesis, Medicine.
Full text available on request.Abstract
Objective: Chronic fatigue syndrome (CFS) and fibromyalgia (FM) are major health problems. Possible factors that may play an etiological role in both CFS and FM are lifestyle factors. Therefore, this thesis examined if there were differences in physical activity or sleep duration in CFS patients, FM patients, and controls. Furthermore, the association between physical activity or sleep duration and the severity of the physical symptoms, and the association between physical activity and sleep duration in CFS and FM patients were examined. Methods: This study was performed in 94,516 participants (age: 44.6±12.5 years, 58.7% female) of the general-population cohort Lifelines. Physical activity was assessed by means of the Short Questionnaire to Assess Health-enhancing physical activity (SQUASH). Furthermore, sleep duration was assessed using the question: “How many minutes do you sleep on average per day?”. Lastly, symptom severity was assessed with the 12-item somatization scale of the Symptom CheckList-90 (SCL-90 SOM). An additional item assessing fatigue was used from the 36-Item Short-Form Health Survey (SF-36). Analyses of covariance were performed to examine the differences in physical activity level and sleep duration. Furthermore, regression analyses were conducted to examine the association between the physical activity or sleep duration and the severity of the physical symptoms, and to examine the association between physical activity and sleep duration. All analyses were adjusted for age, sex, body mass index, smoking, and educational level. Results: CFS and FM patients had a significant lower total activity score (5090±5585 and 5017±5517 MET-minutes/week), compared to controls (5771±5908 MET-minutes/week). Furthermore, CFS patients had the longest sleep duration (460±87 minutes), followed by FM patients (447±75 minutes), and controls had the shortest total sleep duration (440±54 minutes). Additionally, FM patients with higher total activity score reported a lower symptom severity. Quadratic regression analyses indicated that FM patients and controls with moderate total activity score reported a lower symptom severity. Furthermore CFS patients, FM patients and controls with moderate sleep duration reported a lower symptom severity. It was also found that CFS patients and controls with higher total activity score reported a lower sleep duration. Lastly, controls with moderate total activity score reported a lower sleep duration. Conclusion: This thesis revealed that lifestyle factors, including physical activity and sleep duration, are important factors that may play an etiological role in both CFS and FM patients.
| Item Type: | Thesis (Thesis) |
|---|---|
| Supervisor name: | Rosmalen, prof. dr. J.G.M. |
| Faculty: | Medical Sciences |
| Date Deposited: | 25 Jun 2020 10:47 |
| Last Modified: | 25 Jun 2020 10:47 |
| URI: | https://umcg.studenttheses.ub.rug.nl/id/eprint/861 |
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