Koen, Marijke Fijke (2024) Influence of breast cancer on prescribed medication after treatment for breast cancer. thesis, Medicine.
Full text available on request.Abstract
Introduction: In the treatment of breast cancer, various therapies are used, including surgery, chemotherapy and radiotherapy. These treatments may cause (late) side effects such as psychological and physical issues, which sometimes necessitate pharmacological intervention. In this study, we analyzed prescribed medications to determine whether women treated for breast cancer received more medication. Material and Method: This is a retrospective cohort study in which 350 women who were treated with chemotherapy and/or radiotherapy ≥ 5 years ago were compared with 350 age- and general practitioner-matched women without a history of breast cancer. From the general practitioner (GP) files, new prescribed medications, including corresponding Anatomical Therapeutic Chemical (ATC)-codes and medication start dates, were extracted. The primary outcome measure of this study was the number of new prescribed medications in the period following treatment. Secondary analysis compared the type of medication based on ATC categories. Results: Women treated for breast cancer had a higher number of new prescribed medications compared to women without breast cancer (2.0 (IQR 0.0-4.0) vs 1.0 (IQR 0.0-3.0), p=0.013). Additionally, more women treated for breast cancer had one or more new prescribed medications (255 women (72.9%) vs 222 women (63.4%), p=0.007). Furthermore, there were more women treated for breast cancer who had prescribed medications in the ATC categories B, C, L, and M. Conclusion: Women treated for breast cancer received more prescribed medications in the period following treatment compared to women without a history of breast cancer. They were particularly more often prescribed in the medication categories related to blood, cardiovascular issues, hormonal regulation, and musculoskeletal issues.
| Item Type: | Thesis (UNSPECIFIED) |
|---|---|
| Supervisor name: | dr. Brandenbarg, D. and van der Wal, L.T. and dr. Accord-Maass, S.W.M.C. |
| Faculty: | Medical Sciences |
| Date Deposited: | 21 Oct 2024 11:51 |
| Last Modified: | 21 Oct 2024 11:51 |
| URI: | https://umcg.studenttheses.ub.rug.nl/id/eprint/3770 |
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