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Faculty of Medical Sciences

Mogelijkheden om kwaliteit van zorg bij opgenomen patiënten met Acute Kidney Injury (AKI) te verbeteren

Hulter, Suzan (2024) Mogelijkheden om kwaliteit van zorg bij opgenomen patiënten met Acute Kidney Injury (AKI) te verbeteren. thesis, Medicine.

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Abstract

Objective: Acute Kidney Injury (AKI) is a common and serious problem in hospitalized patients. Early recognition and starting of appropriate treatment can reduce the risk of severe complications, such as chronic kidney disease, cardiovascular disease and death. However, research on AKI incidence and quality of care within Dutch hospitals is limited. This research investigates AKI incidence and quality of care within Ziekenhuisgroep Twente (ZGT). Methods: This is a retrospective cohort study within ZGT. AKI was defined based on increase in serumcreatinine, according to the KDIGO guideline. All hospital admissions with AKI were included in a one-year period from October 1st 2022 – October 1st 2023. Admissions of dialysis patients, patients < 18 years old, with a length of stay < 48 hours, and from extramural departments within ZGT were excluded. Data on various aspects of quality of care were collected and analyzed. Results: In total, there were 932 admissions with AKI, the incidence of AKI was 7,0%. AKI was not recognized in 40,9% of the cases. Regarding AKI’s where a hypotensive period was objectified on day of AKI onset, intravenous infusion was not initiated or increased in 64,1% of the cases, and in 39,4% eGFR affecting drugs were not discontinued within one day. In 71,7% of AKI cases where potentially nephrotoxic medication (PNTM) was used, PNTM was not discontinued within one day after AKI onset. Conclusion: AKI is underrecognized and often undertreated. Therefore, it is important to investigate methods for improving AKI quality of care in the future, for example by implementing an ‘AKI-alert’, which automatically recognizes AKI and provides targeted treatment recommendations.

Item Type: Thesis (UNSPECIFIED)
Supervisor name: Prof. Dr. Laverman, G.D. and Dr. Gant, C.M.
Faculty: Medical Sciences
Date Deposited: 08 Oct 2024 13:02
Last Modified: 08 Oct 2024 13:02
URI: https://umcg.studenttheses.ub.rug.nl/id/eprint/3765

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