Bresser, C. C. (2020) Evaluation of uroflowmetry: predictors for non-evaluable uroflowmetry A RETROSPECTIVE COHORT STUDY. thesis, Medicine.
Full text available on request.Abstract
Background: Lower urinary tract symptoms (LUTS) represent a common clinical symptom. LUTS have a major impact on the quality of life. Uroflowmetry (UF) is the most widely used test in the evaluation of LUTS. To obtain representative UF parameters, patients have to void ≥ 150 ml. In practice, this necessity to void ≥ 150 ml turns out to be a significant problem and UF needs to be repeated. Aim: First, we calculated the incidence of non-evaluable UF. Afterwards, we identified patient characteristics that could predict the evaluability of UF measurements, based on the voided volume during UF. Method: This retrospective cohort study consists of 562 patients that underwent UF. The primary outcome was the evaluability of UF, based on a sufficient voided volume (≥ 150 ml). We analyzed patient-specific data, UF data, bladder diary data, and International Prostate Symptom Score (IPSS) data. We performed multiple univariate logistic regressions and multivariate analysis for men and women separately. Results: The average voiding volume recorded in the bladder diary for men was 198 ml, while women presented an average voiding volume of 241 ml. Of all patients, 39.7% voided < 150 ml during UF, resulting in non-evaluable UF. For men, median voided volume during UF was 191.0 ml [105.0- 307.0] while women voided 175.0 ml [97.0-280.0]. For both sexes, a small average voiding volume and high voiding frequency, both recorded in the bladder diary, were significantly associated with a decreased voided volume during UF (OR [95%CI] men respectively 0.99 [0.98-1.00] p = 0.001 and 1.16 [1.01-1.34] p = 0.041, women 0.99 [0.98-1.00] p = 0.007 and 1.28 [1.02-1.61] p = 0.036). Conclusion: The incidence of non-evaluable UF is 39.7%. In both women and men, a small average voiding volume and high voiding frequency, recorded in the bladder diary, are significantly associated with a decreased voided volume during UF. However, because of weak associations, the clinical relevance for these results is probably limited.
| Item Type: | Thesis (UNSPECIFIED) |
|---|---|
| Supervisor name: | Leliveld-Kors, Dr. A.M. and Noordzij, Dr. M.A. |
| Faculty: | Medical Sciences |
| Date Deposited: | 04 Sep 2023 11:29 |
| Last Modified: | 04 Sep 2023 11:29 |
| URI: | https://umcg.studenttheses.ub.rug.nl/id/eprint/3666 |
Actions (login required)
 |
View Item |