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Faculty of Medical Sciences

Sinusoidal vs constant work rate high intensity exercise training in COPD patients with ventilatory limitation

Proos, J. (Jurjen) (2016) Sinusoidal vs constant work rate high intensity exercise training in COPD patients with ventilatory limitation. thesis, Human Movement Sciences.

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Abstract

Background: High intensity exercise during a pulmonary rehabilitation program results in great physiologic benefits in patients with COPD, however these patients often have difficulties to sustain high intensity exercise because of ventilatory limitations. Recently it was shown that COPD patients could exercise at high intensities for a longer period without reaching ventilatory limitations when a sinusoidally varying work rate based on the critical power was used as exercise protocol on a bicycle ergometer. Purpose: The aim of the current study was to determine whether this sinusoidal high-intensity training protocol (ST group) results in a greater physiologic training effect compared to a constant work rate training intervention (CT group) in COPD patients. Methods: The training induced difference in exercise endurance time at a work rate that could be tolerated for 6 minutes before training (ΔtWR6) was compared between both training groups next to parameters for exercise tolerance. In the ST group there were six participants (age: 70 + 8.1, FEV1: 46.7 + 21.3% of predicted) and in the CT group eight participants (age: 63 + 8.1, FEV1: 45.0 + 17.9% of predicted). Both training groups performed an incremental exercise test, pulmonary function tests, four constant work rate tests and a 1-RM test of the quadriceps before and after each of the training programs of 4 weeks. Results: ST and CT groups both improved their ΔtWR6 (improvements of 6.1 + 7.5 minutes in the ST group and 5.1 + 7.7 minutes in the CT group). This increase in endurance time was not significantly different (p = 1) for the two training groups. Furthermore a significant crossover interaction effect (p<0.05) for peak minute ventilation (VEpeak, L/min) and significant main time effects (p<0.05) for VO2peak, VCO2peak, WRpeak, CP, WR6, AT and results of the 1-RM test were found. Discussion: Several improvements in parameters for exercise tolerance following both training programs were found. No parameter however changed significantly more after one training program compared to the other training program. For future research it is suggested to extend the length of both training programs and to increase the group sizes. Keywords: COPD, critical power, exercise tolerance, sine wave, pulmonary rehabilitation

Item Type: Thesis (UNSPECIFIED)
Supervisor name: Vaart, H. van der and Woude, prof. dr. L.H.V. van der
Faculty: Medical Sciences
Date Deposited: 02 May 2022 08:25
Last Modified: 02 May 2022 08:25
URI: https://umcg.studenttheses.ub.rug.nl/id/eprint/3181

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