Veenhuysen, A. (Anouk) (2019) Ecological Momentary Assessment binnen de huisartsenpraktijk: indicatoren van affect als mogelijke voorspellers van verergering van depressieve klachten. thesis, Medicine.
Full text available on request.Abstract
Background: Assessing the course of depression in patients can be a difficult task for general practitioners. In order to provide appropriate treatment, it is important to be able to anticipate the deterioration of symptoms of depression. Possibly this can be done with an innovative method with indicators of affect (autocorrelation, variance and cross-correlation), as obtained with Ecological Momentary Assessment (EMA). The current hypothesis is that the indicators of affect can predict deterioration of symptoms of depression. Objective: The aim of this study was to examine whether EMA indicators can predict the deterioration of symptoms of depression on the longer term in depressed primary care patients. Methods: In a longitudinal prospective cohort study, 17 patients with symptoms of depression or depression rated their mood with EMA in a smartphone app for 10 weeks, with which the indicators of affect were calculated. The outcome measure severity of depression at follow-up after three months was obtained with the Hamilton Rating Scale for Depression 17-items (HRSD-17). Associations between EMA indicators and severity of depression were examined in multiple linear regression analysis. Results: In separate analyses, the indicators autocorrelation (β = 0,542; p = 0,028) and variance (β = 0,622; p = 0,016) of negative affect were significant predictors of the HRSD-17 score at three months, with correction for the HRSD-17 score at baseline. The indicator crosscorrelation between positive and negative affect had no significant association. Conclusion: This study suggests that EMA indicators can provide early warning signals when deterioration of symptoms of depression occurs. Given the limited sample size of this study, outcomes should be considered exploratory.
| Item Type: | Thesis (Thesis) |
|---|---|
| Supervisor name: | Facultair begeleider: and Burger, Dr. H. and Tweede begeleider: and Wouters, Dr. H. and UMCG and Afdeling Huisartsgeneeskunde |
| Faculty: | Medical Sciences |
| Date Deposited: | 25 Jun 2020 10:41 |
| Last Modified: | 25 Jun 2020 10:41 |
| URI: | https://umcg.studenttheses.ub.rug.nl/id/eprint/315 |
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