Doornbos, A. (Adriaan) (2016) VO2peak or oxygen uptake kinetics? A new method to evaluate training based on adaptations at submaximal level in cancer patients. thesis, Sport Sciences.
Full text available on request.Abstract
Introduction: VO2 on-kinetics measured in a constant work rate (CWR) test at moderate intensity is representative of the load coherent with daily life activities and can be used to measure exercise capacity on a submaximal level. VO2 on-kinetics may be more suitable for a deconditioned patient population and a valuable source of information on training effects in addition to the regular exercise tests. Aim: One aim of this study was to examine the effectiveness of the rehabilitation program with respect to optimizing the exercise capacity, performed in cancer patients who completed surgery, radiotherapy and/or chemotherapy at the University Medical Centre Groningen (UMCG), Center for Rehabilitation location Beatrixoord. Also, we wanted to investigate whether VO2 on-kinetics are more sensitive to training-induced adaptations at submaximal level compared to VO2peak and oxygen uptake at the ventilatory anaerobic threshold (VAT) in this population. Methods: Ten cancer patients (7 females) with a variety of cancer types aged between 39 and 64 years were enrolled in a 12-week rehabilitation program, in which they performed combined cycle-ergometer and strength training for two times a week. At initial and final evaluations, VO2 on-kinetics were measured breath-by-breath during a CWR test of moderate intensity, and VO2peak and VAT were measured with an incremental cardiopulmonary exercise test (CPET). Results: Comparisons between pre- and post-intervention showed large effect sizes for VO2peak (r = .59) and oxygen uptake at VAT (r = .56). VO2 on-kinetics did not change after the training program. Conclusion: The training program increased the exercise capacity of the cancer patients. The current results suggest that VO2 on-kinetics is not more sensitive to exercise-induced adaptations compared to VO2peak and VAT. However, VO2 on-kinetics can give useful information on training adaptations, especially when patients have problems performing the maximal exercise obligatory for measuring a valid VO2peak.
| Item Type: | Thesis (UNSPECIFIED) |
|---|---|
| Supervisor name: | Dijk, F. van and Hijmans, dr. J.M. and Vegter, dr. R.K.J. |
| Faculty: | Medical Sciences |
| Date Deposited: | 22 Apr 2022 09:52 |
| Last Modified: | 22 Apr 2022 09:52 |
| URI: | https://umcg.studenttheses.ub.rug.nl/id/eprint/3132 |
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