Cleveringa, M.L.A. (Myrthe) (2020) Long-term hearing outcomes in children with cleft lip and palate. thesis, Medicine.
Full text available on request.Abstract
Background: Patients with cleft palate (CP) and unilateral or bilateral cleft lip and palate (CLAP) often experience conductive hearing loss due to otitis media with effusion (OME) which results from eustachian tube dysfunction and hypoventilation of the middle ear. Long-term hearing outcomes in children with cleft palate (CP) and cleft lip and palate (CLAP) are lacking. In addition the effect of grommet insertion, improving otitis media with effusion (OME), on longitudinal hearing outcomes is scarce. Methods: Patients with CP and CLAP (24,8% syndromic etiology, 75,2% non syndromic) born between 1997 and 2013 were included in this retrospective collected research. A total of 290 patients (580 ears) with 2 or more hearing tests available were included. Patient demographics, otologic and audiometric data were collected. Pure Tone Average (PTA) thresholds (500, 1000, 2000 and 4000 Hz frequencies) both for bone and air conduction, were calculated for analysis. Results: 39,3 % had CP and 56,2 % had a CLAP. Of the 580 ears, 476 ears were found to be of the affected side of the cleft. The mean air conduction (PTA) at last follow-up was 26.1 dB. No statistically and clinically significant difference was found between the first and last PTA results for air conduction in affected ears (p=0,11). Conclusion: Patients with CP and CLAP were found with a persistent conductive hearing loss of 25dB or more in 39,2% of the patients during last follow-up, highlighting the importance of longitudinal follow-up onto adolescent age. Furthermore, 3 or more sets of grommets were inserted to treat OME.
| Item Type: | Thesis (UNSPECIFIED) |
|---|---|
| Supervisor name: | Wachters, drs. J.E. and Bittermann, dr. A.J.N. and Smit, dr. A.L. |
| Faculty: | Medical Sciences |
| Date Deposited: | 16 Dec 2021 13:33 |
| Last Modified: | 16 Dec 2021 13:33 |
| URI: | https://umcg.studenttheses.ub.rug.nl/id/eprint/2877 |
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