Jaspers, M.E.H. (2013) 3D stereophotogrammetry : a reliable and valid method for measuring scar volume? thesis, Medicine.
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Abstract
Background: Objective evaluation of the scar property volume, improves our ability to quantitatively compare the response to therapeutic methods, and allows monitoring of an individual patient. Current techniques for measuring volume are known to be subjective, invasive or cumbersome, and are often not tested for their clinimetric properties such as reliability and validity. 3D stereophotogrammetry is a potential non-invasive technique for the measurement of volume. Therefore, the aim of this study was testing the reliability and validity of 3D stereophotogrammetry for measuring scar volume. Material and Methods: A total of 51 scars (hypertrophic scars and keloids) of 31 patients were recruited from the scar outpatient clinics in the Red Cross Hospital in Beverwijk and the VU Medical Centre in Amsterdam. To test the reliability, the scars were photographed by two observers. Also, a total of 60 simulated (clay) scars were applied on three different body sites of 20 volunteers (upper leg, lower arm and thorax). These scars were measured by 3D stereophotogrammetry and subsequently weighed to establish a gold standard and test the validity. Results: The reliability of 3D stereophotogrammetry was expressed by an intra-class correlation coefficient (ICC) of 0.991, corresponding to the correlation of measurements between two observers. The coefficient of variation (CV) was calculated to express the relative measurement and was found to be 15%. Data were plotted to visualize the difference between the observers and the limits of agreement were calculated at 0 ± 0.289 x Mean Volume. The correlation between 3D stereophotogrammetry and the gold standard was also found to be high: ICC of 0.979. Conclusion: 3D stereophotogrametry is a reliable and valid method for measuring scar volume, expressed by the ICC. However, the agreement between observers needs to be improved, which implicates this method is more suitable for clinical research than for individual patient monitoring.
Item Type: | Thesis (Thesis) |
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Supervisor name: | Facultair begeleider: ` and Beerthuizen, dr. G.I.J.M. chirurg - Martini Ziekenhuis - Gro |
Supervisor name: | Supervisie: and Stekelenburg, drs. C.M. arts-onderzoeker - Beverwijk and Extern begeleider: and Breederveld, prof. dr. R.S. chirurg - Rode Kruis Ziekenhuis |
Faculty: | Medical Sciences |
Date Deposited: | 25 Jun 2020 11:04 |
Last Modified: | 25 Jun 2020 11:04 |
URI: | https://umcg.studenttheses.ub.rug.nl/id/eprint/2400 |
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