Vrieling, S. (Stephan) (2015) Ervaren vrouwen op de lange termijn na behandeling voor mammacarcinoom meer angst dan vrouwen die niet zijn behandeld voor kanker? thesis, Medicine.
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Abstract
Aim: The aim of this study is to assess whether women who have been treated for breast cancer with chemotherapy and/or radiotherapy experience more and/or more intense symptoms of anxiety in the long term after treatment than women who weren’t diagnosed with cancer. Material and methods: From a population of nearly 42.000 patients in general practice, 98 patients who have been diagnosed with breast cancer at least five years ago and 65 controls without cancer were selected. From the 98 patients with breast cancer, 59 patients were treated with chemotherapy en 39 patients were treated with radiotherapy. The Hospital Anxiety and Depression Scale (HADS) was used to assess levels of anxiety in patients and controls. The prevalence and intensity of anxiety have been compared between the two treatment groups and the control group. Logistic regression has been performed to compare odds ratio’s for a possible anxiety disorder between the groups. The regressions are corrected for age, depression and use of antidepressants in the patient’s history. Results: The median follow-up time was 9.4 years in the chemotherapy group and 10.3 years in the radiotherapy group. The median score for anxiety on the HADS was 4.0 in both treatment groups, as well as in the control group. The percentages of women with a possibly anxiety disorder (score HADS-A ≥ 8) didn’t differ significantly between the groups and were 15.3% in the chemotherapy group, 23.1% in the radiotherapy group and 20% in the control group. The corrected odds ratio’s for a possible anxiety disorder were 0.604 for the chemotherapy group (95% CI: 0,229-1,596) and 1.236 for the radiotherapy group (95% CI: 0,454-3,370). These results also were non-significant. Conclusion: Women who have been treated for breast cancer do not experience significantly more or more intense symptoms of anxiety than women who weren’t diagnosed with cancer, regardless of the type of treatment they’ve undergone.
| Item Type: | Thesis (Thesis) |
|---|---|
| Supervisor name: | Berendsen, mw. dr. A.J. |
| Faculty: | Medical Sciences |
| Date Deposited: | 25 Jun 2020 10:57 |
| Last Modified: | 25 Jun 2020 10:57 |
| URI: | https://umcg.studenttheses.ub.rug.nl/id/eprint/1726 |
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