“Accuracy, trend analysis of and influence on continuous noninvasive hemoglobin monitoring of the Masimo Radical-7 Pulse-CO-Oximeter”

Bommel, R. J. A. van (2014) “Accuracy, trend analysis of and influence on continuous noninvasive hemoglobin monitoring of the Masimo Radical-7 Pulse-CO-Oximeter”. thesis, Medicine.

Text BommelvanRJA.pdf Restricted to Registered users only Download (1MB)

Abstract

Study type: Post-hoc analysis of data obtained from a prospective randomized controlled pilot study. Introduction: Peri-operative blood can lead to anemia (shortage of hemoglobin, or Hb) and hypoxia (lack of adequate oxygen supply in the tissue)endangering patient outcome. To protect and improve patient outcome Hb is measured during surgery using a satellite laboratory analyzer (Hbsatlab method).This method requires invasive blood sampling and must be repeated to detect any alteration in Hb concentration. The Masimo Rainbow Radical-7 Pulse-CO-oximeter is a measuring device capable of continuous noninvasive hemoglobin monitoring (SpHb method). The aim of this thesis was to assess whether the SpHb device is suitable to be used as a stand-alone monitor and/or base for clinical decisions in patients at risk of undetected blood loss during surgery. To achieve this thesis goal the agreement between the SpHb method and the clinical standard Hbsatlab method, as well as the trending ability of the SpHb device were assessed. Methods: For the randomized controlled pilot study 30 patients undergoing elective surgery at risk of undetected blood loss were included and randomized into two groups: a Hbsatlab-group with only the Hb¬satlab values available for the attending anesthesiologist, and a SpHb-group with only the SpHb values available. Agreement between Hbsatlab and SpHb methods was analyzed using Bland-Altman analysis for repeated measurements. Trending ability for the two methods was analyzed using polar plots for changes in sequential paired simultaneous measurements. Results: Mean difference between Hbsatlab and SpHb was -0,32 (0,82) mmol/l. Bland-Altman analysis showed 95% limits of agreement of -1,92 and 1,29 mmol/l. Correlation between Hbsatlab and SpHb was 0,71 (p<0,001). Analysis of the polar plot showed 59% of the data within the 30° ‘zone of desired concurrence’. Conclusion: The Masimo Radical-7 Pulse-CO-oximeter did not seem reliable enough to be used as a stand-alone monitor or the sole basis of clinical decisions in patients at risk of undetected blood loss during surgery.

Item Type:	Thesis (Thesis)
Supervisor name:	Berg, J.P. van den MD and Scheeren, Prof. T.W.L. MD and University Medical Center Groningen (UMCG), The Netherlands and Department of Anaesthesiology
Faculty:	Medical Sciences
Date Deposited:	25 Jun 2020 10:54
Last Modified:	25 Jun 2020 10:54
URI:	https://umcg.studenttheses.ub.rug.nl/id/eprint/1525

Actions (login required)

View Item