Letitre, S.L.L. (Sarah) (2013) “Angst en Depressie bij kinderen met Astma.”. thesis, Medicine.
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Abstract
Introduction: Although there is some evidence in the international literature suggesting a relationship between asthma and psychological co-morbidity, considerable controversy remains about the exact nature and strength of this association. The number of available studies is limited and there are large differences between studies in design, subjects, cultural beliefs and clinical practice. The relevance of these results for the European population is therefore unknown. Objective: In a cross-sectional patient-control study, we investigated the prevalence of psychological symptoms (anxiety, depression and low level of self-esteem), in children with stable, partly or well-controlled persistent asthma and in healthy peers. Methods: Using validated questionnaires (Childhood Depression Inventory (CDI), vragenlijst voor angst bij kinderen (VAK), competentiebelevingsschaal voor kinderen/adolescenten (CBSK/CBSA) en zelfbelevingsvragenlijst voor kinderen (ZBV-K)) we quantified the degree of symptoms of anxiety, depression and low level of self-esteem in 70 patients with asthma recruited from the Princess Amalia Children’s Clinic, and compared them to the scores of a control group of equal size, matched for age, gender and socio-economic status. Results: No significant differences were found in mean scores between our two groups in primary outcome values (anxiety, depression and a low level of self-esteem). With p-values ranging from p=0,387 for difference in anxiety-level (VAK) and a 95% confidence interval (95%CI) of 0,5(0,7 – 1,8), p=0,148 for difference in depression-level (CDI) with a 95%CI of 6,4(-2,3 – 15,2) and p=0,188 for the difference in level of self-esteem (CBSK) with a 95%CI of -0,9(-2,3 – 0,4). (CBSA: p=0,234 with 95%CI of -0,9(-2,3 – 0,6)) Of all the subscales, there was a small, but significant difference in experienced level of competence in the specific area of “behaviour and attitude” (p=0.040) and on the subscale “loneliness” (p=0.017), both being poorer in the asthma group. Comparison of the number of children with scores indicating clinically relevant psychological morbidity did not show statistically significant differences between the two groups. Conclusion: The prevalence of psychological symptoms is not higher in children with well-controlled asthma than in healthy peers. Our results suggest that the association between asthma in childhood and psychological co-morbidity found in other studies may be explained by a suboptimal asthma control or “difficult-to-treat asthma”. There is no reason to screen children with well controlled asthma for psychological co-morbidity.
| Item Type: | Thesis (Thesis) |
|---|---|
| Supervisor name: | Brand, P.L.P. and Groot, E.P. de and Amalia kinderafdeling and Isala klinieken Zwolle |
| Faculty: | Medical Sciences |
| Date Deposited: | 25 Jun 2020 10:50 |
| Last Modified: | 25 Jun 2020 10:50 |
| URI: | https://umcg.studenttheses.ub.rug.nl/id/eprint/1097 |
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