Hiemstra, A. (Annemart) (2015) Endometriosis and adverse pregnancy outcomes: A retrospective cohort study. thesis, Medicine.
![[img]](https://umcg.studenttheses.ub.rug.nl/style/images/fileicons/text.png) |
Text
HiemstraA.pdf Restricted to Registered users only Download (434kB) |
Abstract
Background Endometriosis is a common gynaecological disease characterized by the presence of uterine tissue outside the uterus. Patients frequently report infertility, among other symptoms. In recent years techniques for in vitro fertilisation (IVF) and assisted reproduction techniques (ART) are improving, thereby increasing numbers of women with endometriosis who achieve pregnancy. Since then endometriosis has been linked to adverse pregnancy outcomes, although no definite conclusions have been drawn. Therefore, the aim of this study is to investigate the association between endometriosis and adverse pregnancy outcomes. Methods The present study is a retrospective cohort study in which the pregnancies of 55 women in South Australia with endometriosis were analysed. The results were compared to recordings of births in the state South Australia in 2012 regarding adverse pregnancy outcomes. Results Pregnancies of women with endometriosis more often result in stillbirth compared to women without endometriosis. They are more often complicated by pre-eclampsia, placenta praevia, premature rupture of membranes and preterm birth, and infants are more often small for gestational age. No differences were found regarding pregnancy induced hypertension, gestational diabetes, low birth weight, placental abruption, postpartum haemorrhage and incidence of caesarean section or miscarriage. Discussion Findings are somewhat in support of theories regarding a shared underlying pathological mechanism of endometriosis and several adverse pregnancy outcomes. When results were not significant it could be the result of (methodological) limitations of the study, or lack of understanding of the pathogenesis of endometriosis. Further research is necessary to provide conclusive answers.
| Item Type: | Thesis (Thesis) |
|---|---|
| Supervisor name: | Faculty supervisor: and Klinkert, Dr. Ellen UMCG |
| Supervisor name: | Daily supervisor: and Mol, Prof. Ben University of Adelaide |
| Faculty: | Medical Sciences |
| Date Deposited: | 25 Jun 2020 10:48 |
| Last Modified: | 25 Jun 2020 10:48 |
| URI: | https://umcg.studenttheses.ub.rug.nl/id/eprint/949 |
Actions (login required)
 |
View Item |