Wenzel, H. (Hans) (2012) A Pilot Study to Assess the Feasibility, Design and Methods and the Preliminary Outcomes of a Study to Investigate Physical Activity, Nutritional Status, Fatigue and Quality of Life in Paediatric Cancer Patients. thesis, Human Movement Sciences.
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Abstract
Background Physical activity, nutritional status, fatigue and quality of life have all been studied in paediatric cancer patients but not in one single study. Aim of this study was assessing feasibility of the study design and methods and getting a first insight into the relationships between these variables. Procedure 2 This pilot observational cohort study included cancer patients aged 4 - 17 between May and August 2012. Assessments were scheduled at diagnosis and three weeks later. To assess feasibility refusal rate, missing values, timing of assessments, the participants' experienced trouble and costs were evaluated. Physical activity was measured with the ActiGraph accelerometer; nutritional status with body_ mass index, mid-upper arm circumference and bioelectrical impedance; fatigue with the PedsQL Multidimensional Fatigue Scale; and quality of life with the PedsQL Generic Core Scales and PedsQL Cancer Module. Descriptive statistical analysis included calculations of frequencies and percentages. Results Eight patients between five and 17 years (two female) were included. One patient (11 %) denied participation, 48 ( 4%) values of all questionnaires were missing, two ActiGraph assessments could not be executed exactly at the three week time point, zero patients experienced assessments as being troublesome and costs amounted to $10000. Physical activity, nutritional status, fatigue and quality of life were affected negatively. Relationships could not be evaluated. Conclusion The used study design and methods are a feasible way to assess physical activity, nutritional status, fatigue and quality of life. Relationships between these variables could not be examined due to the small sample size.
| Item Type: | Thesis (Thesis) |
|---|---|
| Supervisor name: | Faculty mentor: and Kamsma, Yvo PhD 1) and 1) Center for Human Movement Sciences, University Medical Ce and Groningen, Groningen and Akker-Scheek, Inge van den PhD 2) and 2Department of Orthopedics, University Medical Center Gronin and Groningen, The Netherlands and Tissing, Wim MD and 3) and 3Department of Pediatric Oncology/Hematology, University Med and University of Groningen, Groningen |
| Faculty: | Medical Sciences |
| Date Deposited: | 25 Jun 2020 10:48 |
| Last Modified: | 25 Jun 2020 10:48 |
| URI: | https://umcg.studenttheses.ub.rug.nl/id/eprint/898 |
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