Huisman, C.C. (2019) Percutaneous Transhepatic Biliary Drainage : an effective treatment in patients with and without dilated bile ducts. thesis, Medicine.
Full text available on request.Abstract
Purpose: to assess the results and complications of percutaneous transhepatic biliary drainage (PTBD) in patients with dilated compared to patients with nondilated bile ducts. Materials and methods: patients who underwent PTBD between July 2016 and December 2018 were included in the study. Patients were divided into two groups based on the absence or presence of bile duct dilatation. Technical success, clinical success, and complications were compared between the two groups in a retrospective analysis. Results: 322 patients underwent a total of 400 primary interventions, 245 with dilated and 155 with nondilated bile ducts. An overall technical success rate of 96.8% was achieved (387/400 primary PTBD’s). Technical success was 99.2% in patients with dilated ducts, which was significantly higher than the technical success of 92.9% in patients with nondilated bile ducts (p=0.001). The clinical success was 90.7% in the dilated and 88.7% in the nondilated bile duct group, with no significant difference between the two groups (p=0.522). In 59.5% of the procedures there was at least one complication. There were 347 grade 1-3 complications, without permanent sequelae. Grade 4-6 complications occurred 7 times. Stent dysfunction was the only complication with a significantly higher rate in patients with nondilated bile ducts (46.2% nondilated vs. 13.4% dilated [p=0.006]). Conclusion: PTBD is an effective treatment, with a slightly lower technical success rate in patients with nondilated bile ducts compared to patients with dilated bile ducts, but similar clinical results. Although complications are common, the majority of complications did not cause permanent sequelae.
| Item Type: | Thesis (Thesis) |
|---|---|
| Supervisor name: | Faculty supervisor: and Bokkers Dr. R.P.H. Radiologist UMCG |
| Supervisor name: | External supervisor: and Delden Prof. Dr. O.M. van Radiologist and Institute: Department of Radiology & Nuclear Medicine Amster |
| Faculty: | Medical Sciences |
| Date Deposited: | 25 Jun 2020 10:47 |
| Last Modified: | 25 Jun 2020 10:47 |
| URI: | https://umcg.studenttheses.ub.rug.nl/id/eprint/809 |
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