Wit, T.N. de (Tessa Niki) (2015) Print tuning bij kinderen met en zonder een familiair risico op dyslexie : een fMRI studie. thesis, Medicine.
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Abstract
During reading acquisition, the brain gets tuned for recognizing letters in contrast to symbol. This is called ‘print tuning’ and results in brain activation in the visual word form area (VWVA) in the fusiform gyrus. The absence of brain activity in the left occipito-temporal cortex, including the visual word form area, is one of the most consistent findings in functional magnetic resonance imaging (fMRI) studies with dyslexia. However, little to nothing is known about children with a familiar risk at reading problems, who have nevertheless normal reading skills. The aim of this research is to investigate if and how brain activity, measured by fMRI, differs in children with a familiar risk at dyslexia with ((FRD), n = 2) and without ((FRND), n = 6) reading problems and a control group ((C), n = 13) during a visual repetition detection task focused on print tuning. This way we can determine if there is normalization of compensation at the brain level of the FRND-group. Normalization means that there will be no difference in brain activity between the control group and de FRND-group, compensation means that the FRND-group uses different brain areas during the task. During the repetition detection task, children watched words, pseudowords, nonwords and symbols and they had to respond if they saw a direct repetition of a stimulus. Accuracy was in all groups significantly different between symbols and the other stimulus types. Response time was comparable for all stimulus types. There was no significant difference between the FRND- and the control group. Contrary to our expectations and without a good explanation, only symbols gave significant brain activation in the control group. Except from extra brain activation in the control group in the left and right lingual gyrus in response to symbols compared to nonwords and letters, the FRND- and the control group did not significantly differ in brain activation patterns. Comparison with the FRD-group was not possible, because of the small group size.
| Item Type: | Thesis (Thesis) |
|---|---|
| Supervisor name: | Maurits Prof. dr. ir. N.M. and Neurologie, Universitair Medisch Centrum Groningen and Maassen Prof. dr. B.A.M. and Dyslexie, Faculteit der letteren and Setten, E.R.H. van MSc. and Dyslexie, Faculteit der letteren |
| Faculty: | Medical Sciences |
| Date Deposited: | 25 Jun 2020 10:46 |
| Last Modified: | 25 Jun 2020 10:46 |
| URI: | https://umcg.studenttheses.ub.rug.nl/id/eprint/725 |
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