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Faculty of Medical Sciences

Effects of two different mechanisms of cell salvage on red blood cell aggregation and deformability inpatients undergoing off-pump coronary artery bypass grafting.

Martinez Anton, A. (Angela) (2015) Effects of two different mechanisms of cell salvage on red blood cell aggregation and deformability inpatients undergoing off-pump coronary artery bypass grafting. thesis, Medicine.

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Abstract

In order to avoid allogenic blood transfusion, cell-salvage, a method of collection, washing and reinfusion of blood lost during major surgery, has become a standard procedure in most hospitals. Different types of cell saving devices are commercially available, and the effectiveness and safety of these devices are well known. However, the effects of the cell saving process on the rheological characteristics of erythrocytes have been less explored. In this study, the effects of the washing process of two different types of cell saver on red blood cell aggregability and deformability were examined in patients undergoing cardiac surgery. After washing the blood, no alterations in the measured rheological parameters were found, which was true for both devices employed. The results are in line with most previous research and support the wide use of cell salvage as a safe alternative to allogenic blood transfusion.

Item Type: Thesis (Thesis)
Supervisor name: Supervision: and Scheeren, Prof. Dr. T.W.L. and Department of Anesthesiology, UMCG
Faculty: Medical Sciences
Date Deposited: 25 Jun 2020 10:43
Last Modified: 25 Jun 2020 10:43
URI: https://umcg.studenttheses.ub.rug.nl/id/eprint/423

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