Mulder, Majorie (2025) Lagere lichaamstemperatuur bij à terme neonaten na opvang met physiological-based cord clamping versus delayed cord clamping bij primaire sectio caesarea: een vergelijkend cohortonderzoek. thesis, Medicine.
Full text available on request.Abstract
Background: In physiological-based cord clamping (PBCC), cord clamping after birth is delayed until the neonate has achieved cardiopulmonary stability. This approach supports a gradual transition, allowing the oxygen-rich placental blood flow to be replaced by the newborn’s own respiration and circulation. Previous studies in preterm infants reported lower body temperatures after PBCC, and early resuscitation tables proved insufficient in maintaining normothermia. This comparative cohort study aimed to investigate the difference in first body temperature between term neonates delivered by primary cesarean section (PCS) and resuscitated using PBCC or delayed cord clamping (DCC). Methods: Neonates in the control group underwent DCC (clamping within 1 minute), while those in the intervention group underwent PBCC (clamping between 3 and 10 minutes after birth). The primary outcome was the first measured body temperature after birth. Statistical analyses were performed to assess the effect of the resuscitation method on the temperature. Results: A total of 120 healthy term neonates born via (PCS) were included. Neonates in the PBCC group had a significantly lower first body temperature (36.45 °C versus 36.62 °C ±0.38, 95% CI: 0.02–0.30 °C, p = 0.029) compared to the DCC group. Similarly, the incidence of hypothermia was significantly higher in the PBCC group (50% versus 30%, p = 0.032). Although birth weight and maternal temperature were also associated with neonatal temperature, PBCC remained a significant predictor of lower temperature after adjustment. Conclusion: Term neonates who underwent PBCC during a PCS had lower first body temperatures and a higher incidence of hypothermia compared to those who received DCC. Despite the potential benefits of PBCC, it is important to carefully consider neonatal risks. Further research into reducing heat loss and ensuring neonatal safety is needed for the continued implementation of PBCC.
| Item Type: | Thesis (UNSPECIFIED) |
|---|---|
| Supervisor name: | Ploegstra, Mark-Jan and Scherpenzeel - de Vries, Machteld van |
| Faculty: | Medical Sciences |
| Date Deposited: | 17 Apr 2026 12:46 |
| Last Modified: | 17 Apr 2026 12:46 |
| URI: | https://umcg.studenttheses.ub.rug.nl/id/eprint/3924 |
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