Mansholt, M. (2025) Treat the Consequence or the Cause? A Retrospective Study of Prostate Deobstruction during Cystolithotripsy in Men with Bladder Stones due to Benign Prostatic Hyperplasia-related Bladder Outlet Obstruction. thesis, Medicine.
Full text available on request.Abstract
Introduction Bladder stones secondary to benign prostatic hyperplasia (BPH)-induced bladder outlet obstruction (BOO) pose a urological dilemma: is stone removal alone sufficient, or should the underlying obstruction be treated simultaneously? This retrospective cohort study aimed to assess whether simultaneous prostate deobstruction during cystolithotripsy (CL) reduces bladder stone recurrence without increasing short-term postoperative complications. Methods A total of 123 men underwent CL for bladder stones secondary to BPH-related BOO between 2009 and 2025. Patients were categorized into CL-alone (n = 55) and combined intervention (CL with prostate deobstruction, n = 68). Primary outcomes were bladder stone recurrence and postoperative complications < 30 days. Results Bladder stone recurrence occurred in 26.5% of the CL-alone group and 11.7% of the combined group (p = 0.046), corresponding to a relative risk reduction of 56% and a number needed to treat (NNT) of 7. Postoperative complication rates did not differ significantly between groups (29.1% CL-alone vs. 20.6% combined intervention; p = 0.275). During follow-up, repeat cystolithotripsy was significantly more common in the CL-alone group (22.4% vs. 5.0%, p = 0.007), prostate deobstruction was performed in 22.4% vs. 3.3% (p = 0.002). Conclusion Simultaneous prostate deobstruction during CL is associated with reduced recurrence rates and fewer secondary interventions, without an increase in short-term complication rates.
| Item Type: | Thesis (UNSPECIFIED) |
|---|---|
| Supervisor name: | Oostenbrugge, Dr. T.J. van |
| Faculty: | Medical Sciences |
| Date Deposited: | 08 Apr 2026 14:18 |
| Last Modified: | 08 Apr 2026 14:18 |
| URI: | https://umcg.studenttheses.ub.rug.nl/id/eprint/3917 |
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