Oude Vrielink, T.C. (2024) ASSESSING NUTRITIONAL STATUS AND ENERGY EXPENDITURE IN RELATION TO DIETARY INTAKE IN PATIENTS WITH INFLAMMATORY BOWEL DISEASES: A comparative study in the clinical and outpatient. thesis, Medicine.
Full text available on request.Abstract
in clinical/outpatient patients with active IBD and IBD in remission, in relation to caloric and qualitative nutritional intake. Methods: A single center prospective cohort study was performed in which disease activity, nutritional status (BIVA; Fat-Free Mass Index (FFMI), Phase Angle (PhA)), energy requirement (Q-NRG; Resting Energy Expenditure (REE)), protein requirement and caloric/protein intake were evaluated in 24 patients with active IBD (clinical: n=14, outpatient: n=10) and 11 controls with IBD in remission. Data collection was conducted at baseline (active disease (study group) and control group) and repeated after a 12-week period (remission (study group)) following remission-induction therapy and nutritional interventions. Results: After a 12-week period, a significantly higher increase in FFMI and PhA was observed in the clinical group compared to the outpatient group. In the clinical group, FFMI increased by 1.3 kg/m2 (16.0±0.3 (SE) vs. 17.3±0.4 (SE)), whereas in the outpatient group, the increase was 0.4 kg/m2 (17.5±0.4 (SE) vs. 17.9±0.4 (SE)) (p=0.018). Additionally, PhA increased by 1.3° in the clinical group (5.5±0.2 (SE) vs. 6.8±0.2 (SE)), while in the outpatient group, it increased by 0.1° (6.8±0.3 (SE) vs. 6.9±0.2 (SE)) over the same period (p=0.009). The decrease in REE was equal among the clinical (2016.7± 89.3 (SE) vs. 1926.7± 123.5 (SE)) and outpatient groups (1741.0±104.0 (SE) vs. 1683.3±132.1 (SE)) (p=0.851). Conclusion: There is a notable improvement in FFMI and PhA in the clinical group after remission induction therapy and nutritional interventions, however energy expenditure remains stable in both groups during active disease and remission. Particularly for the clinical group, the current screening/dietary interventions are highly relevant to improve nutritional status.
| Item Type: | Thesis (UNSPECIFIED) |
|---|---|
| Supervisor name: | dr. Mensink, P.B.F. and dr. van Haaften, W.T. |
| Faculty: | Medical Sciences |
| Date Deposited: | 15 Nov 2024 13:24 |
| Last Modified: | 15 Nov 2024 13:24 |
| URI: | https://umcg.studenttheses.ub.rug.nl/id/eprint/3781 |
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