van Engelenhoven, M.H. (2024) AutoCart® behandeling bij osteochondrale laesies van de talus: een goed idee? thesis, Medicine.
Full text available on request.Abstract
Background: Osteochondral lesions of the talus (OLT) result in chronic pain in the ankle during weight-bearing activities. 70% of patients have a traumatic ankle injury in history. In about half of the cases, surgical intervention is not required. The decision to operate depends on the size and location of OLT. Various surgical techniques are available, but an optimal treatment strategy for lesions larger than three cm² with a Berndt & Harty classification IV and V is lacking. This study investigates the effect of the AutoCart® procedure, in which involves filling defects with a mixture of autologous cartilage and platelet rich plasma. Methods: This study is a retrospective cohort study conducted in the orthopedic department of Martini Ziekenhuis Groningen, including nine patients with radiologically confirmed, symptomatic osteochondral lesions of the talus treated with AutoCart® in the past two years. The primary outcomes measured were postoperative satisfaction and secondary outcomes is pain scores Results: The average satisfaction with the surgical outcome was rated a six (0-10, ± 2.7 SD) at a mean follow-up of ten months (± 3 SD). The average pain score at rest decreased from four (± 2 SD) to two (± 2 SD, p = .35). During weight-bearing, the pain score decreased from an average of five (± 2 SD) to three (± 2 SD, p = .67). The preoperative pain associated with OLT was resolved in seven out of nine patients (78%). AutoCart® bij OLT 2 Stage wetenschap 2024 Conclusion: Considering 77% of patients are satisfied with the outcome of the surgery and pain scores were reduced by almost 50%, the AutoCart® treatment appears to be a valuable option for patients with OLT with a Berndt & Harty classification IV and V. Keywords: Osteochondral lesions of the talus, AutoCart®, biological, talar.
| Item Type: | Thesis (UNSPECIFIED) |
|---|---|
| Supervisor name: | Dr. van Raaij, T.M. |
| Faculty: | Medical Sciences |
| Date Deposited: | 16 Sep 2024 11:33 |
| Last Modified: | 16 Sep 2024 11:33 |
| URI: | https://umcg.studenttheses.ub.rug.nl/id/eprint/3758 |
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