Joustra, Maaike Mae (2020) COVID-19 in patients with cutaneous immune-mediated disorders in The Netherlands: real-world observational data. thesis, Medicine.
Full text available on request.Abstract
BACKGROUND: Literature about the incidence, clinical course and psychological burden of COVID-19 in patients with a cutaneous immune-mediated disease treated with systemic immunosuppressive, immunomodulatory or topical treatment is scarce. OBJECTIVES: The aim of this study is to investigate the incidence and clinical course of COVID-19 related symptoms and the effect of the COVID-19 pandemic on clinical and psychological symptoms in patients with atopic dermatitis (AD) and psoriasis vulgaris (PsO). METHODS: We conducted a questionnaire-based cross-sectional study at the department of Dermatology of the Erasmus MC University Medical Center (Rotterdam, The Netherlands) between May 28th 2020 and June 23th 2020. RESULTS: In total, 347 AD patients and 264 PsO patients completed the questionnaire (response rate: 54%). The majority (n=339; 55%) were treated with systemic treatment. Forty-four percent of all respondents experienced at least 1 symptom that might be suggestive of COVID-19. There was no significant difference in the number and nature of COVID-19 related symptoms and cutaneous clinical condition between respondents with or without systemic treatment. Three respondents (0.5%) tested positive for COVID-19, resulting in hospitalization in 1 respondent. Twenty-nine percent of our respondents experienced a feeling of vulnerability in times of COVID-19 pandemic, and 74% reported an increase in their level of stress/anxiety. Respondents with systemic treatment were found to feel more vulnerable compared to respondents without systemic treatment (P <0.01). CONCLUSION: No significant differences were found in the incidence and clinical course of COVID-19 related symptoms between different treatment groups. The psychological burden of the COVID-19 pandemic might however be increased in patients with systemic treatment.
| Item Type: | Thesis (UNSPECIFIED) |
|---|---|
| Supervisor name: | Dr. de Wijs, L.E.M. and Dr. Hijnen, D.J. and Dr. Njoo, M.D. |
| Faculty: | Medical Sciences |
| Date Deposited: | 28 Nov 2023 13:15 |
| Last Modified: | 28 Nov 2023 13:15 |
| URI: | https://umcg.studenttheses.ub.rug.nl/id/eprint/3726 |
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