Bel, Ilse (2020) Het verbeteren van astmacontrole bij kinderen met ongecontroleerd astma door middel van directe feedback op inhalatietechniek en therapietrouw. thesis, Medicine.
Full text available on request.Abstract
Introduction: Asthma is the most common childhood chronic condition in industrialized countries and causes recurrent episodes of wheezing, coughing and dyspnoea. Despite treatment with inhaled corticosteroids (ICS) some children still suffer from uncontrolled asthma. Therapy adherence and inhalation technique of many children is too poor to ensure reliable administration of the medication. This study investigates whether it is possible to improve asthma control in children with uncontrolled asthma by optimizing their adherence and inhalation technique by providing immediate smart feedback. Methods: In this prospective study, two children with uncontrolled asthma were analysed. In the first observational phase, adherence and inhalation technique were registered by the RespiroTM. During the second phase, participants received feedback on their inhalation errors in a web portal after each inhalation. The primary endpoint was clinical improvement, determined by using seven criteria and analysed with a binomial test. As secondary study parameter, the effect of feedback on inhalation technique and adherence was analysed using a Wilcoxon Signed Ranks test. This substudy is part of the IMAGINE-I study. Results: Therapy adherence was high prior to the intervention. Both patients have improved clinically. The differences found are all numerical. Both patients have improved on both peak inspiratory flow (PIF) and duration, but not on orientation of the inhaler. The overall inhalation technique and the number of effective inhalations have not improved. Conclusion: Based on this study, there seem to be opportunities to improve asthma control in children with uncontrolled asthma by providing immediate smart feedback on inhalation technique and adherence. Analyses with larger numbers of patients within the IMAGINE-I cohort could confirm this hypothesis.
| Item Type: | Thesis (UNSPECIFIED) |
|---|---|
| Supervisor name: | Thio, MD PhD., B.J. and Sportel, E.T. |
| Faculty: | Medical Sciences |
| Date Deposited: | 16 Aug 2023 11:27 |
| Last Modified: | 16 Aug 2023 11:27 |
| URI: | https://umcg.studenttheses.ub.rug.nl/id/eprint/3630 |
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