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Faculty of Medical Sciences

1 The Prevalence of Abdominal Complaints in Patients with Severe Psychiatric Disorders

Basahih, Alyazaid (2020) 1 The Prevalence of Abdominal Complaints in Patients with Severe Psychiatric Disorders. thesis, Medicine.

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Abstract

Introduction: BD and SZ are severe mental disorders that cause struggles in interpersonal relationships, occupational and social functioning. Recently, there is a growing interest in abdominal complaints in psychiatric patients. Emerging data reveals a link between psychiatric disorders and IBS. This link can be partly clarified by the bi-directional mechanism of the BGA-axis, which may be influenced by intestinal microbiota. Additionally, influential contributing factors to the development of IBS are gender, fiber consumption and the use of certain medications. Material and methods: The main study parameter was to determine whether the prevalence of abdominal complaints occur more often in psychiatric patients. Psychiatric diagnosis was established by means of medical history and confirmed using the MINI. Abdominal complaints was scored using the GSRS. Furthermore, additional questionnaires were taken including: BPRS, My Medicines & Me Questionnaire and Eating Score Questionnaires Results: a total of 10 patients and 10 control subjects have filled in the GSRS questionnaire. The mean age of the patient and the control group were 42 years old and 39 years old, respectively. Data analysis shows that psychiatric patients suffer more from abdominal complaints. Moreover, a clear gender discrepancy has been observed. Additional influential factors to IBS are fiber consumption and water intake and the use of certain medications. Conclusion: Our data establishes a link between psychiatric disorders and IBS. This link may be partly clarified by the BGA bi-directional pathway. Intestinal microbiota seems to play a role in IBS, and female predominance is observed in IBS patients. Factors that could contribute to this discrepancy may be of biological, behavioral, psychological, and possible sociocultural differences between men and women. Additionally, factors such as diet and medication use seem to contribute to IBS symptomology.

Item Type: Thesis (UNSPECIFIED)
Supervisor name: Sommer, prof. dr. I.E.C.
Date Deposited: 11 Aug 2023 11:41
Last Modified: 11 Aug 2023 11:41
URI: https://umcg.studenttheses.ub.rug.nl/id/eprint/3622

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