Alotaibi, Norah (2020) Diagnostic errors in clinical FDG-PET/CT scans: lessons learned. thesis, Medicine.
Full text available on request.Abstract
Purpose: To determine the frequency, types, and determinants of diagnostic errors in clinical FDGPET/ CT, based on addenda to the original report. Materials and Methods: This retrospective study included 4,099 consecutive clinical FDG-PET/CT scans with corresponding reports that were made at the University Medical Center Groningen in an 18- month period. FDG-PET/CT reports were scrutinized for the presence of an addendum enclosing a diagnostic error. Results: 90 of 4,099 FDG-PET/CT reports (2.2%) contained an addendum enclosing a diagnostic error. The distribution of perceptual and cognitive errors among these 90 diagnostic errors was 54 (60.0%)/36 (40.0%). On multivariate logistic regression analysis, only low-dose FDG-PET/CT combined with concomitantly acquired and interpreted full-dose contrastenhanced CT remained as significantly and independently associated with the presence of a diagnostic error, relative to low-dose FDG-PET/CT without concomitantly acquired and interpreted full-dose contrast-enhanced CT (odds ratio of 2.79 [95% confidence interval: 1.61-4.85], P<0.001). Patient age, gender, and hospital status, indication for FDG-PET/CT scanning, single vs. double reading, reader experience, and reading by a nuclear medicine physician only vs. reading by both a nuclear medicine physician and a radiologist, were not significantly and independently associated with the presence of a diagnostic error. Conclusion: Diagnostic errors in clinical FDG-PET/CT based on addenda to the original report are relatively infrequent, though certainly non-negligible. Perceptual errors are slightly more frequent than cognitive errors. The availability of a concomitantly acquired and interpreted full-dose contrast-enhanced CT seems to increase diagnostic error rate. These data can be used for quality improvement and benchmarking purposes.
| Item Type: | Thesis (UNSPECIFIED) |
|---|---|
| Supervisor name: | Kwee, T. and Yakar, D. |
| Faculty: | Medical Sciences |
| Date Deposited: | 28 Jul 2023 11:13 |
| Last Modified: | 28 Jul 2023 11:13 |
| URI: | https://umcg.studenttheses.ub.rug.nl/id/eprint/3603 |
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