Leusink, Marle (2021) Lange termijneffecten van handvaardigheidstraining op intracorticale inhibitie; een TMS studie. thesis, Dentistry.
Full text available on request.Abstract
In literature, there is little known about the long-term effect of motor learning. To develop motor dexterity, dentistry student receive manual dexterity training during their study. This creates a unique opportunity to measure the long-term effects of training on corticospinal excitation and cortical inhibition. The aim of this study is to understand whether motor learning leads to change in the primary motor cortex (M1). Better understanding of motor learning can help to improve education in the future. The first question is whether there is a difference in excitation and inhibition between the students who have and have not received manual dexterity training. The second question is whether there is a relationship between the Purdue Pegboard data and the inhibition and excitation of M1. The manual dexterity level was quantified by the results of the Purdue Pegboard test. The results of 14 first-year dentistry students have been compared with the results of 12 firstyear medical students. The medical students did not receive manual dexterity training in the first year of the study and acted as a control group. Parameters of motor excitation and inhibition have been assessed using a transcranial magnetic stimulator (TMS) to evoke a 4 recruiting curve and short-latency intracortical inhibition (SICI). The parameters were obtained while the subject's hand was at rest (resting) and during a small background activity (active). The repeated measures ANOVA for SICI and the recruiting curve showed no difference between groups and in time. The Pearson's correlation showed no association between SICI and manual dexterity. The Pearson's correlation, however, showed a relationship between the change in manual dexterity level over time and the rest recruiting curve steepness (r = .46; p = .03), active recruiting curve amplitude (r = - .43; p = .03) and active recruiting curve steepness (r = .40; p = .045). These parameters are a measure of the excitability of M1. It can be concluded that there is an association between the overtime change in excitability and manual dexterity level of the student. Follow-up research on the subject is desirable. In that case, including a larger study population is advisable.
| Item Type: | Thesis (UNSPECIFIED) |
|---|---|
| Supervisor name: | Zijdewind, Dr. C.A.T. |
| Faculty: | Medical Sciences |
| Date Deposited: | 04 Apr 2023 11:14 |
| Last Modified: | 04 Apr 2023 11:14 |
| URI: | https://umcg.studenttheses.ub.rug.nl/id/eprint/3466 |
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