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Faculty of Medical Sciences

Physical Activity in Patients with Chronic Low Back Pain: The relation between central sensitization and objectively measured physical activity

Vettorato, S. (Sabrina) (2018) Physical Activity in Patients with Chronic Low Back Pain: The relation between central sensitization and objectively measured physical activity. thesis, Human Movement Sciences.

Full text available on request.

Abstract

Purpose The main objective of this study is to analyse the relation between Central Sensitization (CS) symptoms’ severity and Physical Activity (PA). The secondary objectives are: to explore if CS severity levels are related to PA and to compare the Physical Activity Levels (PALs) distribution between the CS severity levels. Methods The study included patients with Chronic Low Back Pain (CLBP). The CS symptom severity was assessed with Central Sensitization Inventory (CSI) while PA was measured during a full week with a tri-axial accelerometer (ActiGraph). To analyse the relation between CS severity and PA, a regression analysis was performed. To explore the relation between CS severity levels and PA, a regression analysis was performed. To test the distribution of the different PALs between CS severity levels, a MANOVA was performed. Results 27 patients (age: 42.3 (±11.0); CSI: 38.3 (±11.2)) were included in the analysis. On average, patients had 534621.0 (±208536.9) counts/day, spending the 55.4% of the time in sedentary PA, 38.4% in light activity, and 6.2% in moderate-to-vigorous PA. The relation of CS severity and PA was absent (R2=0.002, p=0.808). The relation of CS severity levels and PA was absent for any of the levels (R2=0.141, Mild: p=0.122; Moderate: p=0.966; Severe and Extreme: p=0.420). The PALs distribution did not differ among the CS levels (F (9, 51.26) = 1.300 (p = 0.260); partial η2 = 0.154), with very similar distribution between the all the CS severity levels. Conclusion A relation between CS and PA was not found in the current results. Explorative analysis revealed that CS severity levels do not differ in PA, neither in PALs distribution. Therefore, CS symptoms’ severity is not sufficient to explain PA. Other factors, besides CS symptom severity, could explain better the relation between CS and PA, due to the possible inter-individual and multifactorial essence of CLBP. Keywords physical activity; central sensitization; accelerometry; chronic low back pain

Item Type: Thesis (UNSPECIFIED)
Supervisor name: Echeita, J.A. and Reneman, dr. M.F. and Lamoth, dr. C.J.C.
Faculty: Medical Sciences
Date Deposited: 24 May 2022 10:02
Last Modified: 24 May 2022 10:02
URI: https://umcg.studenttheses.ub.rug.nl/id/eprint/3434

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