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Faculty of Medical Sciences

A randomized controlled pilot study on the effects of combined resistance training and cognitive training on executive function in elderly with mild cognitive impairment

Hamse, M. (Mirte) (2015) A randomized controlled pilot study on the effects of combined resistance training and cognitive training on executive function in elderly with mild cognitive impairment. thesis, Human Movement Sciences.

Full text available on request.

Abstract

Background: A strong risk factor for dementia is mild cognitive impairment (MCI). People with MCI show cognitive decline but are still capable of daily self-care, whereas people with dementia need more care and are often institutionalised. Interventions are needed to slow down ageing processes in the brain of elderly with MCI. The aim of this randomized controlled pilot study is to investigate the effects of a combined resistance training (RT) and cognitive training (CT) program on executive function in older persons with MCI Method: 25 elderly with MCI were randomly assigned in 3 groups to an 8-week twice-weekly program, 1: RT + CT (n=12), 2: RT (n=5), 3: Control (n=8). The primary outcome measure was executive function, measured in 8 tests. The secondary outcome measure was physical condition, measured in 7 tests. Results: Between-group analysis revealed a significant moderate to large effect in strategy planning in favour of both experimental groups, as well in selective attention & conflict resolution in favour of the RT group. Also a significant large effect was found in leg strength in favour of the RT group. Conclusion: The results showed that some domains of executive function could benefit from intervention of combined RT and CT or RT only, namely strategy planning and selective attention & conflict resolution. Also leg strength can benefit from RT. Future research should focus on larger groups, optimized training programs (in different stages of cognitive decline) and underlying mechanisms.

Item Type: Thesis (UNSPECIFIED)
Supervisor name: Heuvelen, dr. M.J.G. van and Hortobagyi, prof. dr. T.
Faculty: Medical Sciences
Date Deposited: 12 Apr 2022 07:30
Last Modified: 12 Apr 2022 07:30
URI: https://umcg.studenttheses.ub.rug.nl/id/eprint/3085

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