Galama, M. (2015) Effect and dose-response relationship of a two intensity 8-week combined aerobic and strength training program on cognitive and motor function in people with early stage dementia. thesis, Human Movement Sciences.
Full text available on request.Abstract
Introduction: Currently, worldwide 35.6 million people suffer from dementia and this number will increase rapidly in the next coming years. It is suggested that physical activity could be a treatment modality for the dementia related cognitive and physical deterioration. This study examined both the effect and dose-response relationship of a two intensity eight-week combined aerobic and strength training intervention on cognitive and physical functioning in older adults with early stage dementia. Method: Five older adults with early stage dementia participated in this randomized controlled trial (n = 5, mean age: 76.8 ± 4.1; mean Mini-Mental-State-Examination score: 15.4 ± 2.6). Exercise group (n=3) performed three training sessions per week, consisting alternating of strength exercises and walking exercises. The first four weeks consisted of low intensity training, followed by four weeks of high intensity training. The control group (n=2) received recreational sessions, consisting of easy board games, puzzles and playing with a balloon. Baseline- , half-way and post-measurements consisted of a neuropsychological and physical test battery in the following domains: memory, processing speed, executive functioning, leg strength, walking endurance, maximal gait speed, balance and functional mobility. Results: Participants who received exercise training improved or remained stable on the Stroop color-word task and TMT-A task after the intervention period. The participant who received recreational sessions showed no improvement in cognitive functioning. All participants showed mixed positive and negative effect of exercise training on physical functioning. However, leg strength and walking endurance improved more during the high intensity phase then during the low intensity training. Conclusion: A combined training intervention of aerobic and strength training results in positive changes in cognitive functioning. Data suggest a positive dose-response relationship between exercise intensity and leg strength capacity and walking duration. However, long-term randomized controlled trials are needed, with a large number of participants, to confirm current assumption.
| Item Type: | Thesis (UNSPECIFIED) |
|---|---|
| Supervisor name: | Heuvelen, M.J.G. van |
| Faculty: | Medical Sciences |
| Date Deposited: | 08 Apr 2022 13:39 |
| Last Modified: | 08 Apr 2022 13:39 |
| URI: | https://umcg.studenttheses.ub.rug.nl/id/eprint/3081 |
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