Wenzler, O.P.B. (Otmar) (2021) Herhaalde digitale subtractie-angiografie bij angio-negatieve niet-perimesencephale subarachnoïdale bloedingen. thesis, Medicine.
Full text available on request.Abstract
Background: A repeat digital subtraction angiography (DSA) is regarded as the golden standard in patients with a non-perimesencephalic subarachnoid hemorrhage (SAH) after negative baseline imaging. Nevertheless, a DSA has a substantial risk of severe neurological complications. The aim of this study is therefore determining the detection rate of repeat DSA. Methods: The data is extracted from databases with SAH patients of two medical centers, namely the Isala Clinics (Zwolle) and the UMCG (Groningen). The extracted data is used to compose a new database with patients with an angio-negative non-perimesencephalic SAH. With this newly created database the detection rate of repeat DSA will be calculated and an overview of patient characteristics is displayed. Results: The databases of the Isala Clinics and the UMCG together contained 1372 SAH patients. 84 of the 1372 patients (6,1%) met the inclusion and exclusion criteria. 54 of the 84 patients (64,3%) underwent a repeat DSA. In 3 of the 54 patients (5,6%) repeat DSA identified a causative lesion. Conclusion: The observed detection rate of repeat DSA was 5,6% in patients with non-perimesencephalic SAH. Therefore, a repeat DSA is still warranted in patients with non-perimesencephalic SAH after negative baseline imaging despite the risk of complications of a DSA. A prospective comparison between a repeat computed tomography angiography (CTA) and a repeat DSA is needed to determine if a repeat CTA could replace a repeat DSA in the diagnostic work-up of patients with non-perimesencephalic SAH after negative baseline imaging.
| Item Type: | Thesis (UNSPECIFIED) |
|---|---|
| Supervisor name: | Dijk, prof. dr. J.C.M. van and Foumani, drs. M. |
| Faculty: | Medical Sciences |
| Date Deposited: | 07 Jan 2022 08:45 |
| Last Modified: | 07 Jan 2022 08:45 |
| URI: | https://umcg.studenttheses.ub.rug.nl/id/eprint/2981 |
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