Ponds, N.H.M. (Noa Helena Maria) (2021) Long-term Quality of Life outcome after spondylodiscitis treatment. thesis, Medicine.
Full text available on request.Abstract
BACKGROUND CONTEXT: Spondylodiscitis is the most common spinal infection of which the incidence has increased and the peak prevalence is between 50 and 70 years of age. Spondylodiscitis is often a complication of a distant infection. Early diagnosis can be challenging, and although improvements in diagnostic techniques and modern therapy have diminished the mortality of the disease, current literature about the outcome of spondylodiscitis is scarce. PURPOSE: To evaluate the long-term clinical outcome of patients who suffered from spondylodiscitis. STUDY DESIGN: A two-center cross-sectional study. PATIENT SAMPLE: Patients with spondylodiscitis in two large teaching hospitals in the Netherlands between 2003 and 2017. OUTCOME MEASURES: Visual Analogue Scale (VAS) for back pain, Oswestry Disability Index (ODI) for disease specific quality of life, and Short Form 36 (SF-36) for general quality of life of spondylodiscitis patients. METHOD: Eligible patients were identified from electronic patient databases and completed multiple patient reported outcome measures after obtaining informed consent. General demographic and clinical information (age, sex, medical history) were extracted from the patient records. SF-36 domain scores of spondylodiscitis patients were compared with a nationwide population sample. RESULTS: 192 patients were treated for spondylodiscitis; additional questionnaires were received from 82 patients. The overall mortality was 27%. The mean VAS for back pain was 3.5, and the mean ODI-score was 22. In all SF-36 domains a significantly lower score was found in the spondylodiscitis group compared with a normative national Dutch cohort. There was a strong correlation between back pain and ODI-scores (r = 0.81, p < 0.05). CONCLUSIONS: Our study confirms that spondylodiscitis is a disease causing a profound impact on back pain and quality of life. The results suggest that chronic back pain is a debilitating problem, as it has an extensive influence on daily activities and social and psychological well-being, causing significant disability. Keywords: spondylodiscitis, long-term, clinical outcome, back pain, quality of life, Oswestry Disability Index, Short Form 36
| Item Type: | Thesis (UNSPECIFIED) |
|---|---|
| Supervisor name: | Delawi, dr. D. and Wolterbeek, dr. N. and Bolink, dr. S.A.A.N. |
| Faculty: | Medical Sciences |
| Date Deposited: | 04 Jan 2022 10:16 |
| Last Modified: | 04 Jan 2022 10:16 |
| URI: | https://umcg.studenttheses.ub.rug.nl/id/eprint/2930 |
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