Deelstra, F. S. (Femke Suzanne) (2021) Significante achteruitgang van de cognitieve functie bij 65-plussers na electieve vaatchirurgie: Op moment van ontslag uit het ziekenhuis is de cognitieve functie significant slechter dan preoperatief. thesis, Medicine.
Full text available on request.Abstract
Introduction: Partly due to the ageing population, the proportion of surgical patients ≥65 years is increasing. Within the vascular surgery population, this proportion is particularly high, since atherosclerosis, an important etiological factor for many vascular diseases, increases with age. The effect of a vascular intervention on cognitive function has not been sufficiently studied before. Therefore, this study focuses on pre- and postoperative changes in cognition in elderly vascular surgery patients. Method: This observational cohort study includes patients of ≥65 years old with an indication for elective vascular surgery. Cognitive function, measured with the Montreal Cognitive Assessment (MoCA), was assessed preoperatively, at discharge, and 4-8 weeks postoperative during follow-up. A score <25 was referred to as Mild Cognitive Impairment (MCI). Results: A total of 29 patients were included. Preoperatively, MCI was found in 34.5%, at discharge in 70.8% and during follow�up in 50.0% of the patients. The mean MoCA score was preoperatively 25.4, at discharge 22.6 and 25.1 during follow-up. The mean MoCA score was significantly lower during discharge than preoperatively (p=0.004). There is a significant correlation between this change in MoCA score and the variables Comprehensive Complication Index (p=0.027), preoperative CRP (p=0.026), and BMI (p=0.027). Discussion&Conclusion: At the time of discharge, cognitive function in elderly patients appears to be significantly worse compared to the preoperative measurements. More results are needed about the transition of cognitive function after vascular surgery, as well as the contribution of pre-operative and peri-operative patient characteristics to determine the actual effect and possibility to intervene.
| Item Type: | Thesis (UNSPECIFIED) |
|---|---|
| Supervisor name: | Pol, dr. R. A. and Banning, L. B. D. |
| Faculty: | Medical Sciences |
| Date Deposited: | 23 Dec 2021 14:11 |
| Last Modified: | 23 Dec 2021 14:11 |
| URI: | https://umcg.studenttheses.ub.rug.nl/id/eprint/2896 |
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