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Faculty of Medical Sciences

Dietary intake and gastrointestinal complaints in patients with schizophrenia and bipolar disorder: What does the gut say?

Badawi, A.S. (2020) Dietary intake and gastrointestinal complaints in patients with schizophrenia and bipolar disorder: What does the gut say? thesis, Medicine.

Full text available on request.

Abstract

Introduction: Currently, there is accumulating evidence on the influence of the gastrointestinal system on the pathophysiology of schizophrenia (SCZ) and bipolar disorder (BD). This influence might be related to dietary, immune and microbiome-related factors. Objective: The objective was to examine dietary intakes, as assessed by the Food Frequency questionnaire (FFQ), in participants of the GUTS study compared to matched controls. Methods: 34 participants diagnosed with SCZ, BD, or schizoaffective disorder (SAD) were matched to controls from the LifeLines Biobank according to age, sex, body mass index (BMI) and income. Dietary items were categorized and scored as FFQ-related estimates. Results: More GUTS participants followed a vegetarian or vegan diet (n=16) than controls (n=6). The GUTS participants consumed more vegetables (p<0.0001) and less meat or poultry (p=0.012), compared to controls. Conclusion: The results of this study can be explained by the difference in vegetarianism and education in the two groups. Furthermore, by the low level of psychopathology in the GUTS participants.

Item Type: Thesis (UNSPECIFIED)
Supervisor name: Sommer, prof. dr. I. (Iris) and Borkent, J. (Jenny)
Faculty: Medical Sciences
Date Deposited: 16 Dec 2021 15:13
Last Modified: 16 Dec 2021 15:13
URI: https://umcg.studenttheses.ub.rug.nl/id/eprint/2883

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