Ligthart, I.A. (2019) De voorspelbaarheid van de noodzaak van pre-radiotherapeutische extracties in relatie tot hoofd-hals tumoren. thesis, Dentistry.
Full text available on request.Abstract
Purpose Patients with head and neck cancer who will be treated with radiation therapy (RT) are seen for a pre-radiation dental screening to eliminate oral foci to minimize the risk on developing osteoradionecrosis (ORN). Up to 40 Gy the risk of developing ORN is low, so eliminating oral foci would not be necessary if the RT dose is <40 Gy. However the RT dose is not known before the pre�radiation dental screening. In this retrospective study we assessed the number of eliminated foci with a low-dose of RT and the possibilities to predict the RT dose for specific parts of the jaw using tumor stadium and location. Methods All dentate patients > 18 years, diagnosed with primary oral or oropharyngeal carcinoma, referred for pre-treatment dental screening between May 2011 and May 2013, were included. The presence of every tooth, foci, extractions, the RT dose of specific points in the jaw and the development of ORN were recorded. Results 30,52% of all extractions were unjustified, in the upper anterior region even 41,67% of the extractions were unjustified. The tumor properties, location, lymph nodes, T-classification, did predict the RT-dose, but did not exclude the possibility of a RT dose >40 Gy. Conclusions After a pre-radiation dental screening too many teeth are extracted, especially in the upper anterior region. However it is not possible to predict the RT dose using tumor properties.
| Item Type: | Thesis (UNSPECIFIED) |
|---|---|
| Supervisor name: | Witjes, Dr. M.J.H. and Reintsema, dr. H. and Stokman, dr. M.A. |
| Faculty: | Medical Sciences |
| Date Deposited: | 23 Nov 2021 15:36 |
| Last Modified: | 23 Nov 2021 15:36 |
| URI: | https://umcg.studenttheses.ub.rug.nl/id/eprint/2851 |
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