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Faculty of Medical Sciences

De effectiviteit van fluoride op de remineralisatie van tandglazuur bij de thuisbleekbehandeling: een in vitro studie

Oosterzee, M.L. van (2018) De effectiviteit van fluoride op de remineralisatie van tandglazuur bij de thuisbleekbehandeling: een in vitro studie. thesis, Dentistry.

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Abstract

Introduction External tooth bleaching is an effective approach to whiten teeth. However, bleaching agents can damage the enamel. This can be observed by a decrease in enamel microhardness. Incorporation of fluoride has a positive effect on the microhardness of enamel. The aim of this study is to evaluate the microhardness of enamel after repeatedly applying fluoride during bleaching procedures. Materials and methods In this study, 96 enamel samples were allocated to four research groups and bleached with a fluoride bleaching gel for 8 hours a day, for a period of 10 days. During bleaching, each group was treated with either 500 ppm fluoride dentifrice (group 1, FT500), 1450 ppm fluoride dentifrice (group 2, FT1450), 5000 ppm fluoride dentifrice (group 3, FT5000) or received no further treatment (group 4, control group). Initial measurements (t=0), after measurements (t=15) and final measurements (t=23) were obtained using the Knoop hardness meter. The results were statistically analyzed using the one way ANOVA and the mixed design ANOVA. Results The one way ANOVA did not show a significant effect between all four groups (F(3,92)=1.990; p=0.121) at the initial measurements (t=0). The mixed design ANOVA showed there was a statistically significant interaction effect between group and time on microhardness (F(6, 178)= 5.547, p= .000). A simple effects analysis was conducted, which showed that group 1 (FT500) and group 3 (FT5000) had a significant increase in microhardness compared to the control group, with a p-value of respectively p= .001 and p= .019. Group 2 did not show a significant increase in microhardness (p=.545). Conclusion This study suggests that topical fluoride treatment during dental bleaching procedures has a delayed positive effect on the microhardness of enamel. Treatment with respectively 500 ppm fluoride and 5000 ppm fluoride where most effective. Further research is necessary to demonstrate the possible delayed effects of fluoride during dental bleaching procedures.

Item Type: Thesis (UNSPECIFIED)
Supervisor name: Hoogmoed, dr. C.G. van and Geertsema - Doornbusch, ing. G.I.
Faculty: Medical Sciences
Date Deposited: 23 Nov 2021 12:23
Last Modified: 23 Nov 2021 12:23
URI: https://umcg.studenttheses.ub.rug.nl/id/eprint/2824

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