Comparison between the childhood health assessment questionnaire (CHAQ) and the CHAQ38 with the childhood myositis assessment scale (CMAS) in children with juvenile dermatomyositis (JDM).

Overkamp, I. (Ilse) (2010) Comparison between the childhood health assessment questionnaire (CHAQ) and the CHAQ38 with the childhood myositis assessment scale (CMAS) in children with juvenile dermatomyositis (JDM). thesis, Human Movement Sciences.

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Abstract

Objective. To compare the relationship between the original Childhood Health Assessment Questionnaire (CHAQ) and the CHAQ38 with the Childhood Myositis Assessment Scale (CMAS) in a population of children with Juvenile Dermatomyositis (JDM), throughout their disease course. Methods. In this retrospective study, original CHAQ and CHAQ38 scores from 50 patients with JDM (20 c3'; 30 Sj?) were matched with CMAS scores at 4 time periods of the disease. The mean age of the patients at diagnosis date was 7.6 ± 3.5 (range 3.0 - 15.4 years). Bivariate and partial (controlled for age) correlations were calculated at the 4 periods. Results. At time of diagnosis (± 1 month), both the original CHAQ and the CHAQ38 showed a high correlation with the CMAS, with the CHAQ38-CMAS correlation (r = -.960, p < .005) being higher than the original CHAQ-CMAS correlation ( -.805, p < .05). When controlled for age, the original CHAQ-CMAS correlation was not significant, however, the CHAQ38- CMAS correlation remained significant (r = -.966, p < .005). At period 2, 3 and 4 (6 - 27 months after diagnosis), the correlations between both versions of the CHAQ and the CMAS decreased, with bivariate correlations ranging from .032 to -.652 and partial correlations ranging from -.418 to -.631, with higher original CHAQ-CMAS correlations. Conclusion. During active disease, the CHAQ38 seems to be a better instrument to use in clinical practice for patients with JDM.

Item Type:	Thesis (Thesis)
Supervisor name:	Mouton, L.J. MSc
Supervisor name:	Brussel, M. van MSc and Child Development and Exercise Center and Wilhelmina Children's Hospital, University Medical Center Ut
Faculty:	Medical Sciences
Date Deposited:	25 Jun 2020 11:07
Last Modified:	25 Jun 2020 11:07
URI:	https://umcg.studenttheses.ub.rug.nl/id/eprint/2704

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