Booij, C. (Coen) (2013) Verificatie functioneel afkappunt voor trismus bij hoofdhals oncologie patienten. thesis, Dentistry.
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Abstract
Purpose: Verify the functional cut-off point for trimsus of S35mm in a group of head and neck oncology patients, which had not been used earlier for this purpose, and analyse if there is a difference in cut-off point for trismus among: dentate, partially dentate and edentate patients. Patients and methods: In 122 patients mouth opening was measured and they were asked if they experienced problems with their mouth opening according to question 10 of the EORTC QLQ-H&N35. Based on the answers three criteria were created: Criterion 1: "not at all" versus "a little" to "very much", Criterion 2: "not at al" and "a little" versus "a lot" and "very much" and criterion 3: "not at all" to "a lot" versus "very much". The specificity, sensitivity and the percentage of correctly predicted patients were calculated for the cut-off points 1 Omm to 40mm, according the three criteria, for the total group and subgroups by the use of receiver operating characteristic (ROC) curves. Results: The mean mouth opening for the total group (n=1 09) was 40.2 mm (95% Cl: 37.6 tot 42.5) of which 43% experienced a little to very much difficulty with opening their mouth. The AUC for criterion 1 was 0.702 (95o/o Cl: 0.598;0.805), criterion 2 was 0.805 (95% Cl: 0.683;0.926) and criterion 3 was 0.830 (95% Cl: 0.639;1 ). Criterion 2 was selected as criterion for trismus based on the analysis and clinical judgement. The percentage correctly predicted was highest for the cut-off point's S29 up to and including S32mm (86-87%). The subgroups turned out to be too small for a statistical analysis. Conclusion: In this study a range of cut-off points for trismus of S29 up to and including S32mm was found, there is only a minor difference compared to the earlier proposed cut-off point of S35mm. Influence by dentition couldn't be determined.
| Item Type: | Thesis (Thesis) |
|---|---|
| Supervisor name: | Dijkstra, Prof. Dr. P.U. |
| Faculty: | Medical Sciences |
| Date Deposited: | 25 Jun 2020 11:07 |
| Last Modified: | 25 Jun 2020 11:07 |
| URI: | https://umcg.studenttheses.ub.rug.nl/id/eprint/2692 |
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