Oosterhoff, M. (2012) De kindercontusie : een beschrijvende studie. thesis, Medicine.
Full text available on request.Abstract
Aim. The purpose of this study is to describe a group of children with the 'juvenile head trauma syndrome', focussing on age of presentation, the clinical symptoms, possible abnormalities of cerebral imaging and the progression in time of this phenomenon, using inclusion new-established criteria. Also to analyze possible risk factors for the 'juvenile head trauma syndrome' – mainly focussing on headache and migraine – as an expression of a genetic predisposition for hemiplegic migraine. Study design. A prevalence study. Methods. We collected children with traumatic brain injury by means of diagnosis codes and screened them for presence of the 'juvenile head trauma syndrome' using our inclusion criteria. We arranged a revision of the children who met the criteria. We collected the necessary information using a questionnaire and conducted a neurological examination. Also, we reassessed the radiological imaging data. Results. Out of a total of 570 children with a brain concussion in the period 01/01/2008 to 09/12/2011 we collected nineteen children with the 'juvenile head trauma syndrome', which we divided into three separate groups. The age at the time of head injury averaged at 7.1 years, the lucid interval averaged at 61.9 minutes, the decrease in consciousness averaged at 56.3 minutes and the total duration averaged at 7.3 hour. The variations were large in all the variables however. Most of the events of the 'juvenile head trauma syndrome' occurred after a fall from a bike or after a fall on the ground after tripping. The clinical symptoms were found to differ greatly in children aged two to four years – with a lowering of consciousness or somnolence, sometimes accompanied by headache or vomiting – compared with older children – with changes in consciousness often accompanied by focal clinical symptoms, and sometimes no changes in consciousness at all – and often there was a gradual progression in the clinical course. None of the children met the criteria for migraine and none met the criteria for the periodic syndromes in childhood. In the first-degree relatives 17% of the males and 44% of the women were having migraine. Together, 11% of the first-degree relatives were having migraine with aura symptoms. Conclusions. The 'juvenile head trauma syndrome' is a relatively rare phenomenon that not only presents in early childhood. The clinical symptoms are very variable. To really test the possible relationship between hemiplegic migraine and the 'juvenile head trauma syndrome' a larger sample is needed together with genetic research.
| Item Type: | Thesis (Thesis) |
|---|---|
| Supervisor name: | Facultair begeleider; and Hageman, dr G. Neurologie and Medisch Spectrum Twente |
| Faculty: | Medical Sciences |
| Date Deposited: | 25 Jun 2020 11:06 |
| Last Modified: | 25 Jun 2020 11:06 |
| URI: | https://umcg.studenttheses.ub.rug.nl/id/eprint/2629 |
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