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Faculty of Medical Sciences

Wat is het effect van de botuline toxine type A behandeling bij kinderen met een kwijlprobleem?

Dijkstra, F. (Frank) (2009) Wat is het effect van de botuline toxine type A behandeling bij kinderen met een kwijlprobleem? thesis, Dentistry.

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Abstract

Drooling is the uncontrolled loss of saliva by different causes. Possible causes of drooling are medication, change of teeth, tooth decay or gum inflammation, a swallowing disorder, a conservation or movement disorder or an abnormal shape or size of the jaw and I or tongue. Drooling can occur in all age groups and is often associated with a disease or a mental limitation. Drooling can be treated in several ways: posture exercises, a swallowing training and I or speech therapy, medication or surgery. These treatments are known for having disadvantages. It is now also possible to inject botulinum toxin type A in the salivary glands in children with a drooling problem. Botulinum toxin type A (BTX-A) has emerged as a potential treatment for the management of drooling. BTX-A inhibits the incentive transfer of cholinergic nerve endings to the salivary gland. This prevents secretion of saliva. The purpose of this literature study is to determine whether the treatment of children with a drool problem through the injection ofBTX-A in the salivary glands is an effective treatment. The consulted studies differed in design of the study, used doses ofBTX-A and used methods of measurement. All studies showed that BTX-A is a good solution for the drooling problem and no side effects were demonstrated. It can be concluded that the treatment ofBTX-A injections in parotid, submandibulaire or in both salivary glands is an effective and safe method to reduce drooling in children with a drooling problem. This treatment also improves the quality of life of children with a drooling problem. To put the treatment ofBTX-A injections in children with a drooling problem in a proper place between the longer-existing therapies, more research need to be conducted on the effects ofBTX-A treatment in the long term.

Item Type: Thesis (Thesis)
Supervisor name: Begeleiders: and Blanksma, N.G. and afdeling kindertandheelkunde aan de faculteit tandheelkunde and Parree, J.W.F. afdeling kindertandheelkunde aan de faculteit
Faculty: Medical Sciences
Date Deposited: 25 Jun 2020 11:06
Last Modified: 25 Jun 2020 11:06
URI: https://umcg.studenttheses.ub.rug.nl/id/eprint/2621

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