Rijn, R.L.J. van (Robin) (2012) Weefselreactie rond titanium- en zirconia- implantaatopbouwen in de mens. thesis, Dentistry.
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Abstract
Purpose This research focuses on the difference between the quantitative degree of inflammation on histological level and qualitative degree of inflammation in soft-tissue surrounding titanium- and zirconia-abutments three months post-operatively in humans. Materials and Methods Twenty edentulous subjects received two titanium implants with a zirconia- and a titanium-abutment in the mandibula. In 17 of 20 people biopsies were taken 3 months postoperatively. The first technique used resulted in too much sacrifice of soft-tissue, as a result there's been decided to use a different technique for the remaining 14 patients. From the tissue surrounding each implant a mesial and distal biopsy was taken. From these biopsies, coupes were made and were stained with collagen IV staining. These sections were assessed for the quantitative (measured in number of blood vessels per 40 000 um²) and qualitative (number of fibroblasts and inflammatory cells per coupe is estimated on clinical judgment arranged on four levels) degree of inflammation. Results Quantitative: The averages of measurement 1 and 2 taken for titanium-abutments were 21.3 (sd=4.3) and for zirconia-abutments 21.7 (sd=3.1) blood vessels per 40,000 um². This difference was not significant (t=-0.4, df=12, p=0.72). The 95% confidence interval around the mean difference between the two groups was -2.6 to 1.8. Qualitative: The average for the qualitative data were for titanium-abutments 3.1 (sd=0.6) and zirconia-abutments 3.2 (sd=0.6). This difference was not significant (t=- 0.8, df=12, p=0.44). The 95% confidence interval around the mean difference between the two groups was - 0.6 to 0.3. Conclusions No histological difference could be demonstrated between both the quantitative and qualitative degree of inflammation in the soft-tissue surrounding titanium-and zirconia-abutments three months post-operatively in humans.
| Item Type: | Thesis (Thesis) |
|---|---|
| Supervisor name: | Begeleiders: and Cune Prof. dr. M.S. (Universitair Medisch Centrum Groningen |
| Faculty: | Medical Sciences |
| Date Deposited: | 25 Jun 2020 11:05 |
| Last Modified: | 25 Jun 2020 11:05 |
| URI: | https://umcg.studenttheses.ub.rug.nl/id/eprint/2460 |
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