Boersma, K. (Karina) (2015) Preventie van chylothorax als complicatie bij oesofagusresecties. thesis, Medicine.
![[img]](https://umcg.studenttheses.ub.rug.nl/style/images/fileicons/text.png) |
Text
BoersmaA.doc Restricted to Registered users only Download (6MB) |
Abstract
Background. Postesophagectomy chylothorax is a rare and potentially severe complication in patients diagnosed with oesophageal cancer. It is mostly caused by iatrogenic thoracic duct injury. This complication may be prevented by peroperative visualization of the thoracic duct. In this pilot study we evaluated the effects of peroperative enteral administration of methylene blue in visualizing the thoracic duct. Methods. From 15 October 2014 until 15 January 2015, all patients who underwent an esophagectomy according to the principles of the minimally invasive esophagectomy in our centre, received methylene blue through the jejunostomy in the abdominal phase of the operation. Blue discoloration of the thoracic duct was assessed during the thoracoscopic part of the operation. Results. There was no blue discoloration of the thoracic duct in any of the six patients. The primary outcome was 0%, with (95% CI 0-45%) and (99.9% CI 0-72%). The predetermined minimal required therapeutical effect was 90%, which was evidently outside the boundaries of the confidence intervals. Conclusion. Methylene blue does not give blue discoloration of the thoracic duct when administered enterally during esophagectomy. Therefore, methylene blue is not useful in the prevention of chylothorax.
| Item Type: | Thesis (Thesis) |
|---|---|
| Supervisor name: | Pierie, Prof. dr. J.P.E.N. and Medisch Centrum Leeuwarden |
| Faculty: | Medical Sciences |
| Date Deposited: | 25 Jun 2020 10:41 |
| Last Modified: | 25 Jun 2020 10:41 |
| URI: | https://umcg.studenttheses.ub.rug.nl/id/eprint/225 |
Actions (login required)
 |
View Item |