Usefulness of personal counseling in patients with well-differentiated thyroid cancer who follow a low iodine diet because of treatment with radioactive iodine.

Jagersma, R.J. (2015) Usefulness of personal counseling in patients with well-differentiated thyroid cancer who follow a low iodine diet because of treatment with radioactive iodine. thesis, Medicine.

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Abstract

Introduction: Patients with differentiated thyroid cancer (DTC) have to follow an low iodine diet (LID) before radioactive iodine therapy (RAIT). Several studies investigated the duration and the strictness of the LID, but none of them studied the optimal way of preparing patients for the LID. The compliance to the LID differs between patients, as the urinary iodine excretion (UIE) shows a wide variation in patients who all follow the same diet with the same written instructions. The aim of this study was to evaluate if personal counseling by a dietician should be standard care for DTC patients who have to follow an LID. Methods: In this single-center prospective, non-randomized, unblinded study, all patients with DTC were asked if they would get personal counseling. The group that received personal counseling was compared with the group who received written instructions (control group). The primary endpoint was the percentage of DTC patients who reached the goal of UIE < 50 μg/L after one week of LID. Secondary endpoints were blood pressure and complaints. Results: 28 patients were included (counseling group n = 13, control group n = 15). Seven out of ten patients (70%) in the counseling group reached an UIE 50 < μg/L, compared with nine out of eleven patients (82%) in the control group (p = 0.64). Mean systolic blood pressure (n = 21) before diet was 133 ± 17 mmHg compared with 121 ± 15 mmHg at day 7 of the diet (p < 0.001). Patients in the control group (n = 15) had significantly more complaints of dizziness than the counseling group (n = 11) (resp. 67% versus 27%, p = 0.047). Conclusion: In patients who have to follow an LID for one week before RAIT, personal counseling does not have an effect on the UIE, in comparison with standard care.

Item Type:	Thesis (Thesis)
Supervisor name:	Horst-Schrivers, Dr. A.N.A. van der and Links, Prof. dr. T.P. and Swart-Busscher, Mrs. L.G.
Faculty:	Medical Sciences
Date Deposited:	25 Jun 2020 11:02
Last Modified:	25 Jun 2020 11:02
URI:	https://umcg.studenttheses.ub.rug.nl/id/eprint/2239

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