Vogel, M.C. de (2014) Een retrospectieve cohortstudie naar de relatie tussen milde nierarteriestenose en de incidentie van hypertensie. thesis, Medicine.
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Abstract
Introduction: Renovascular hypertension is most commonly caused by an atherosclerotic stenosis. Until now, trials researching renal artery angioplasty have focused on severe renal artery stenosis, with disappointing results. Recently it has been suggested to reconsider the role of moderate stenosis in the development of renovascular hypertension. The aim of this study is to demonstrate that a moderate renal artery stenosis causes significant renovascular problems, showing as an increased incidence of hypertension. Methods: In this retrospective cohort 344 individuals were included who underwent CT-Angiography of the abdominal aorta. The renal arteries were evaluated for the presence of stenosis. The test subjects were allocated as mild/no (<30%), moderate ((≥30-70%) and severe (>70%) based on the severity of stenosis. Afterwards the patients chart was investigated for the presence of hypertension. Results: Of the individuals with mild/no renal artery stenosis (n=208) 67.8% had hypertension. In the group with moderate renal artery stenosis (n=92) 85.9% of the individuals was hypertensive. Severe renal artery stenosis showed an incidence (n=44) of 97.7%. Discussion: The presence of a moderate renal artery stenosis is associated with a significant rise in incidence of hypertension. This finding justifies further evaluation of individuals with a moderate renal artery stenosis for suitability for angioplasty.
| Item Type: | Thesis (Thesis) |
|---|---|
| Supervisor name: | Wottiez, dr. A.J. and Hout, dr. J.H.W. van den and Vestering, drs. M. |
| Faculty: | Medical Sciences |
| Date Deposited: | 25 Jun 2020 11:02 |
| Last Modified: | 25 Jun 2020 11:02 |
| URI: | https://umcg.studenttheses.ub.rug.nl/id/eprint/2219 |
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