Stolker, E. (Ellen) (2015) Meetinstrumenten extrapiramidale bijwerkingen van antipsychotica bij mensen met een verstandelijke beperking. thesis, Medicine.
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Abstract
Background People with intellectual disability often use antipsychotic drugs. Extrapyramidal symptoms are a common side-effect of these drugs. There are a lot of rating scales for extrapyramidal symptoms. In this study we want to investigate whether the subscales parkinsonism/dyskinesia and behaviour/akathisia of the Matson Evaluation of Drug Side-effects (MEDS) are a proper and useful scale for professional caregivers in identifying extrapyramidal symptoms in people with intellectual disability. We will also look for the preference of intellectual disability physicians to use the Abnormal Involuntary Movement Scale (AIMS) or the Dyskinesia Identification System: Condensed User Scale (DISCUS) as rating scale for the presence and severity of tardive dyskinesia. Methods We used a cross-sectional study-design. Participants are 89 residents of an intellectual disability care provider. We compared proportional scores of the MEDS, as judged by the main caregiver, with proportional scores of the Barnes Akathisia Rating Scale (BARS), Unified Parkinson Disease Rating Scale (UPDRS), AIMS and DISCUS, as measured by the ID physician. Results In 10 of the 15 comparisons a significant difference was found between the MEDS and the comparing scale. In all off these cases the proportion of the scale measured by the ID physician was higher than the one of the MEDS. No significant difference was found between the value and needed time of the AIMS and the DISCUS. Conclusion At this point, the MEDS isn’t a good screening instrument for extrapyramidal symptoms as side-effect of antipsychotic drugs in people with an intellectual disability when judged by the main care giver. With training of the main care givers we might be able to improve this. The AIMS and the DISCUS are at this moment for ID physicians equal choices for signalling tardive dyskinesia.
| Item Type: | Thesis (Thesis) |
|---|---|
| Supervisor name: | Kuijper, Dr. G.M.de and Hoekstra, Prof. dr. P. J. and Centrum Verstandelijke beperking en Psychiatrie & Van Boeije |
| Faculty: | Medical Sciences |
| Date Deposited: | 25 Jun 2020 10:59 |
| Last Modified: | 25 Jun 2020 10:59 |
| URI: | https://umcg.studenttheses.ub.rug.nl/id/eprint/1981 |
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