Hijma, C. (Christie) (2012) The impact of early poststroke depression on the trajectory of disability recovery in younger adults: Part of Psychosocial Outcomes in StrokE (POISE) – A prospective cohort study. thesis, Medicine.
Full text available on request.Abstract
Background and Purpose: The purpose of this study was to analyze the predictive value of poststroke depression at baseline (28 days poststroke) on changes in disability recovery after one year poststroke in younger (<65 years) stroke survivors. Depression after stroke is a common problem. About one quarter of people who have had a stroke are younger than 65 years and they have a longer life expectancy and overall better recovery than older stroke survivors. Methods: Psychosocial Outcomes in StrokE (POISE) is an observational cohort study following young (<65 years) stroke survivors. Participants were interviewed at 28 days (baseline), 6 months and 12 months. The World Health Organisation Disability Assessment Schedule (WHODAS) II was used to assess disability and the Hospital Anxiety and Depression Scale (HADS) was used to assess depression and anxiety . Multivariate linear regression was used to make a predictive model for change in disability at 12 months poststroke. Results: 318 participants with complete data on the HADS at baseline and WHODAS-II scores at baseline and 12 months were included in these analyses. 42 (13%) participants had depression at baseline. Only 12 (3.7%) participants were depressed on all three time-points. The HADS-depression score was an important baseline predictors of less change in disability at 12 months. When participants were in paid work or had a history of depression before stroke, they showed greater improvement (reduction) in disability at one year Conclusion: This study showed that depression occurs less in our population compared with previous studies. Patients with acute poststroke depression showed significant improvement in disability over time but were still more disabled than non-depressed participants one year post stroke.
| Item Type: | Thesis (Thesis) |
|---|---|
| Supervisor name: | Faculty supervisor: and Jonge, Prof. Dr. P. de |
| Supervisor name: | Supervisor: and Hackett, Dr. M.L. and The George Institute for Global Health – Australia |
| Faculty: | Medical Sciences |
| Date Deposited: | 25 Jun 2020 10:59 |
| Last Modified: | 25 Jun 2020 10:59 |
| URI: | https://umcg.studenttheses.ub.rug.nl/id/eprint/1944 |
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