Kraats, J. van der (Judith) (2014) Een retrospectieve studie naar het effect van groene groenten, rundvlees, volle melk en roomboter op het lipidenprofiel bij kinderen. thesis, Medicine.
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Abstract
Background: Based on previous studies of the diets of children with recurrent respiratory tract infections, a dietary advice has been developed. This dietary advice contains nutritional foods that support the immune system. The dietary advice comprises the eating of beef 3 times a week, green vegetables 5 times a week, and a daily portion of whole milk en butter. All the other dietary habits remained unchanged. Research shows that the dietary advice had significant positive health effects [3,4]. However, there is concern on the dietary advice because of the use of whole milk. It is thought that the lipid profile will be adversely affected by the use of whole milk products. In a retrospective cohort study, we investigated the effect of the dietary advice on the lipid profile of children. Material and Methods Children aged from 1 to 16 years, of whom two or more times a lipid profile was determined in the period between June 2011 and November 2013, were included in the study cohort. Children who had followed the dietary advice were assigned to the intervention group, the remaining children were assigned to the control group with the exception of children who were excluded based on the excluding criteria. The lipid profile, BMI, and BMI-z-score were determined in both groups. A paired T-test was used for testing the course of the lipid profile, BMI and BMI-z-score for each group. The difference in end value, adjusted for the initial value, between the two groups was assessed by an Ancova test. Shifts of the lipid profiles were assessed with a Mc Nemar. Results In the intervention group, there was a statistical reduction of the cholesterol/HDL ratio (p<0,001) and non-HDL-cholesterol (p=0,038) after following the dietary advice for 3 months. There was also a statistical increase of the HDL-cholesterol (p=0,006) after following the dietary advice for 3 months. The difference in the end value of the cholesterol/HDL ratio and HDL cholesterol between the control and intervention group, adjusted for the initial value was significantly different. The cholesterol/HDL ratio in the intervention group was significantly more reduced (p=0,013) compared to the control group. The HDL-cholesterol in the intervention group was significantly more increased (p=0,040) compared to the control group. In the intervention group, a significant shift towards normalization of cholesterol/HDL ratio (25%, p=0,003) and HDL-cholesterol (35,4%, p=0,003) occurred. The dietary advice had no effect on BMI and BMI-z-score. In the control group, there were no significant changes. Conclusions A change of diet towards green vegetables, beef, whole milk and full-fat butter has no adverse effect on the lipid profile, BMI and BMI-z-score in children. In fact under influence of the dietary advice a significant beneficial effect on the lipid profile occured. The dietary advice not only has a proven positive effect on the immune system, this study shows that it causes a normalization in the lipid profile. The dietary advice can therefore be safely recommended. The assumption of the American Heart Association does not apply to our targeted group.
| Item Type: | Thesis (Thesis) |
|---|---|
| Supervisor name: | Gaag, drs. E. van der and ZiekenhuisGroep Twente and locatie Hengelo and Afdeling Kindergeneeskunde |
| Faculty: | Medical Sciences |
| Date Deposited: | 25 Jun 2020 10:59 |
| Last Modified: | 25 Jun 2020 10:59 |
| URI: | https://umcg.studenttheses.ub.rug.nl/id/eprint/1920 |
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