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Faculty of Medical Sciences

Determinanten van xerostomie en hun samenhang met orale candidiasis : Een literatuuronderzoek

Hassani Katesari, T. (2009) Determinanten van xerostomie en hun samenhang met orale candidiasis : Een literatuuronderzoek. thesis, Dentistry.

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Abstract

Xerostomia is defined as having a dry mouth due to lack of saliva. It is unpleasant and has a negative effect on the quality of life for sufferers. The treatment of xerostomia is aimed at relieving associated symptoms and the prevention of complications. Oral candidosis is a complication of xerostomia, which may lead to additional oral complaints and dysfunction. Oral candidosis can be treated with antifungal medicines, but preventive measures can decrease the chance of developing oral candidosis. There are still obscurities concerning the determinants of xerostomia and their consistency with oral candidosis. This is a literature study concerning the possible determinants of xerostomia and their consistency with oral candidosis. The question as to whether these same determinates caused candidosis without provoking xerostomie was also investigated. De aims where to find answers to the following questions: a. What are the determinants of xerostomia and do these have a relationship with candidosis? b. Would these determinants also be able to cause oral candidosis without causing symptoms of xerostomia? During this study the search engine "Web of Science' was used to make a selection of scientific articles concerning determinants of xerostomia and their relationship with oral candidosis. Research has shown that different determinants including medication, radiation therapy of the head and neck region, systemic diseases such as primary and secondary Sjogren's syndrome, diabetes mellitus and progressive kidney disease reduce salivary flow and can thus lead to both xerostomia and oral candidosis. Medication and diseases which impair the immune system (HIV/AIDS), can cause oral candidosis directly without causing xerostomia. Additionally, smoking, wearing dentures, lack of oral hygiene, age and poor nutrition of the patient can also play a role in causing oral candidosis, without causing symptoms of xerostomia.

Item Type: Thesis (Thesis)
Supervisor name: Juch, Dr. P.J.W. and Universitair Medisch Centrum Groningen and Centrum voor Tandheelkunde en Mondzorgkunde
Faculty: Medical Sciences
Date Deposited: 25 Jun 2020 10:57
Last Modified: 25 Jun 2020 10:57
URI: https://umcg.studenttheses.ub.rug.nl/id/eprint/1776

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