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Faculty of Medical Sciences

Antibiotics and Antibiotic Resistance : Knowledge, awareness and behaviour

Vries, S.S. de (Sabina) (2016) Antibiotics and Antibiotic Resistance : Knowledge, awareness and behaviour. thesis, Medicine.

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Abstract

Antibiotic resistance is a major and worldwide threat to both human and veterinary health care and asks for a multidisciplinary approach. As part of this so called ‘One Health approach’ in the first part of this study we aimed to get more insight in the knowledge, awareness and behaviour of medical students from the Netherlands (N=39) and veterinary students from the Netherlands (N=33) and South Africa (N=38), and South African veterinarians (N=28), by using an online questionnaire. Medical students had a higher score on the questions about knowledge about antibiotics and resistance than veterinary students and Dutch students had a higher score than South African students. All the students had a good knowledge level and were properly aware of the problem of antibiotic resistance. Unfortunately their behaviour was not always in line with their knowledge, because sometimes they did not finish their antibiotic treatment or kept the leftovers. The number of South African veterinarians that responded was too low to draw reliable conclusions, but the data suggests a lack of knowledge, but a good awareness. Within the problem of antibiotic resistance, one of the most pressing threats in human health care as well as in veterinary health care is the rapid emergence and spread of Extended Spectrum Betalactamases (ESBLs). Therefore in the second part of this study we aimed to gain more knowledge on the occurrence of ESBL in areas where antibiotics are not or hardly used. The amount of ESBL producing E.coli was determined in faecal samples of cattle in the Mnisi Community, South Africa. No ESBL producing E.coli were demonstrated, indicating that there is no or less ESBLs in the (almost complete) absence of antibiotics. This suggests that decreasing the amount of antibiotics used, will be the most effective measure to decrease the emergence and spread of ESBLs.

Item Type: Thesis (Thesis)
Supervisor name: Second supervisor: and Nijholt, dr. I.M. Zwolle
Supervisor name: First supervisor: and Vuuren, prof. M. van Department of Veterinary Tropical Disea
Faculty: Medical Sciences
Date Deposited: 25 Jun 2020 10:56
Last Modified: 25 Jun 2020 10:56
URI: https://umcg.studenttheses.ub.rug.nl/id/eprint/1672

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